75630-46-5Relevant academic research and scientific papers
The Chemistry of Pyrrolic Compounds. LXV Intramolecular Cyclization of Porphyrins with Acetic Acid Chains: Hydroxy Derivatives of Deoxophylloerythroaetioporphyrin (DPEP)
Clezy, Peter S.,Mirza, Aminul H.,Prashar, Jognandan K.
, p. 857 - 866 (2007/10/02)
The intramolecular cyclization of porphyrins substituted with an acetic acid side chain has been studied under a range of conditions but the yield of product bearing a fused five-membered ketonic ring system was disappointingly low.Deoxophylloerythroaetio
Biosynthesis of Porphyrins and Related Macrocycles. Part 13. Structure of the Protoporphyrin Isomer derived from Coproporphyrinogen lV by the Action of Beef-Liver Coproporphyrinogenase: Synthesis of Protoporphyrin Xlll
Battersby, Alan R.,Hamilton, Andrew D.,McDonald, Edward,Mombelli, Luisa,Wong, Oi-Hoong
, p. 1283 - 1289 (2007/10/02)
Coproporphyrinogen lV (8) is synthesised and is oxidatively decarboxylated by coproporphyrinogenase from beef-liver to produce, after aromatisation, a porphyrin proved to be protoporphyrin Xlll (11) by spectroscopy and by unambiquous synthesis; the synthesis route is described.A monovinylporphyrin, derived from an intermediate for the conversion (8) -> (11), is also isolated.The importance of these results for earlier biosynthetic studies with pyrromethanes is discussed.
