75640-69-6 Usage
Uses
Used in Pharmaceutical Research and Development:
(R)-3,3'-DIBROMO-2,2'-DIMETHOXY-1,1'-BINAPHTHYL is used as a chiral ligand and catalyst for the synthesis of enantiomerically pure compounds, which is essential in the creation of pharmaceuticals with specific biological activities. Its ability to catalyze asymmetric reactions ensures the production of desired enantiomers, contributing to the development of more effective and safer medications.
Used in Organic Chemistry:
In the field of organic chemistry, (R)-3,3'-DIBROMO-2,2'-DIMETHOXY-1,1'-BINAPHTHYL serves as a key chiral ligand and catalyst, facilitating the synthesis of complex organic molecules with high optical purity. This is particularly important in the synthesis of natural products and the development of new materials with specific properties.
Used in Asymmetric Synthesis:
(R)-3,3'-DIBROMO-2,2'-DIMETHOXY-1,1'-BINAPHTHYL is utilized as a chiral catalyst in various asymmetric reactions, enabling the selective formation of one enantiomer over another. This selective synthesis is crucial for the production of chiral molecules with high optical purity, which are often required in applications such as pharmaceuticals, agrochemicals, and fragrances.
Used in Transition Metal-Catalyzed Reactions:
As a chiral ligand, (R)-3,3'-DIBROMO-2,2'-DIMETHOXY-1,1'-BINAPHTHYL is employed in transition metal-catalyzed reactions to impart enantioselectivity and control the stereochemistry of the products. This application is vital in the synthesis of complex chiral molecules with potential applications in various industries, including pharmaceuticals, materials science, and specialty chemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 75640-69-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,6,4 and 0 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 75640-69:
(7*7)+(6*5)+(5*6)+(4*4)+(3*0)+(2*6)+(1*9)=146
146 % 10 = 6
So 75640-69-6 is a valid CAS Registry Number.
75640-69-6Relevant academic research and scientific papers
Oxidation of BINOLs by Hypervalent Iodine Reagents: Facile Synthesis of Xanthenes and Lactones
Wirth, Thomas,Zhang, Huaiyuan
supporting information, (2022/03/17)
Xanthene derivatives have broad applications in medicines, fluorescent probes, dyes, food additives, etc. Therefore, much attention was focused on developing the synthetic methods to prepare these compounds. Binaphthyl-based xanthene derivatives were prepared through the oxidation of BINOLs promoted by the hypervalent iodine reagent iodosylbenzene (PhIO). Nine-membered lactones were obtained through a similar oxidative reaction when iodoxybenzene (PhIO2) was used. Additionally, one-pot reactions of BINOLs, PhIO and nucleophiles such as alcohols and amines were also investigated to provide alkoxylated products and amides in good to excellent yields.
Chiral Mo-binol complexes: Activity, synthesis, and structure. Efficient enantioselective six-membered ring synthesis through catalytic metathesis
Zhu, S. Sherry,Cefalo, Dustin R.,La, Daniel S.,Jamieson, Jennifer Y.,Davis, William M.,Hoveyda, Amir H.,Schrock, Richard R.
, p. 8251 - 8259 (2007/10/03)
A new class of chiral Mo-based complexes 2a and 2b, bearing functionalized chiral binol ligands, is disclosed. Mo complex 2a promotes the asymmetric ring-closing metathesis (ARCM) of various dienes and trienes to afford six-membered carbo- and heterocycle
Host-Guest Complexation. 23. High Chiral Recognition of Amino Acid and Ester Guests by Hosts Containing One Chiral Element
Lingenfelter, David S.,Helgeson, Roger C.,Cram, Donald J.
, p. 393 - 406 (2007/10/02)
The chiral recognition properties of ten enantiomerically pure hosts toward the enantiomers of six different amino acids and their methyl esters have been examined.The hosts possessed the general structure (A)2D(OEOEO)2E, in which D is the chiral 1,1'-din
