756431-07-9

Upstream product

• 3392-10-7 tert-butoxycarbonyl-L-proline N-hydroxysuccinimide ester 
• 84794-48-9 Boc-Ala-Pro-Tyr-OMe 
• 19669-38-6 tert-butyl (2S)-2-{[(2S)-3-(4-hydroxyphenyl)-1-methoxy-1-oxopropan-2-yl]carbamoyl}pyrrolidine-1-carboxylate 

Downstream Products

• 84794-53-6 Ac-Pro-Ala-Pro-Tyr-OMe 

Relevant academic research and scientific papers

Serine-Protease-Assisted Synthesis of Peptide Substrates for α-Chymotripsin

δ-Chymotrypsin catalyzes peptide-bond formation between acylated amino-acid and peptide esters as the carboxyl component and amino-acid and peptide amides as the amino component.The conditions under which enzyme-catalyzed coupling can be used for fragment condensation in peptide synthesis is investigated.To illustrate the method the synthesis of tetra-, penta and hexapeptides of the structure Ac-Lxn-...-Lxl-Lyl-...-Lym-NH2 with Lxl = Tyr, designed as substrates for α-chymotrypsin is described.