756459-04-8

Upstream product

• 69567-11-9 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol 
• 219717-72-3 N--2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol 
• 219717-73-4 N--2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol 
• 205649-25-8 [(1R,2R,3S,4R,5S)-3,4,5-Tris-(tert-butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-2-hydroxy-cyclopentyl]-carbamic acid benzyl ester 
• 205649-23-6 [(1R,2R,3S,4S,5S)-4,5-Bis-(tert-butyl-dimethyl-silanyloxy)-2-(tert-butyl-dimethyl-silanyloxymethyl)-2,3-dihydroxy-cyclopentyl]-carbamic acid benzyl ester 
• 219717-67-6 N-(3-aminopropyl)-2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol 
• 203130-19-2 <1R-(1α,2β,3α,4β,5β)>-1-(tert-butyldimethylsilyloxymethyl)-5-isothiocyanato-2,3,4-tris(tert-butyldimethylsilyloxy)cyclopentan-1-ol 
• 203130-18-1 <1R-(1α,2β,3α,4β,5β)>-5-amino-1-(tert-butyldimethylsilyloxymethyl)-2,3,4-tris(tert-butyldimethylsilyloxy)cyclopentan-1-ol 
• 151061-97-1 trehazolamine 
• 219717-74-5 N-<3-<1R-(1α,2β,3α,4β,5β)>-<<1-(tert-butyldimethylsilyloxymethyl)-1-hydroxy-2,3,4-tris(tert-bityldimethylsilyloxy)cyclopent-5-yl>aminothiocarbonyl>aminopropyl>-2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol 

Downstream Products

• 203130-28-3 N-<2-<<1R-(3aα,4α,5β,6α,6aα)>-4-hydroxymethyl-3a,5,6,6a-tetrahydro-4,5,6-trihydroxy-4H-cyclopentoxazol-2-yl>aminopropyl>-2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol 

Relevant academic research and scientific papers

Syntheses of 1-Deoxynojirimycin-Trehalamine-Fused and -Linked Compounds and Their Biological Activities

1-Deoxynojirimycin-trehalamine-fused and -linked compounds (10,19a and 19b) were synthesized from 1-deoxy-2,3,4,6-tetra-O-benzylnojirimycin and trehazolamine, which was obtained from natural trehazolin as a degradation product. None of these synthetic compounds exceeded 1-deoxynojirimycin in the inhibitory activities towards rat intestinal maltase and yeast α-D-glucosidase. - Keywords: Aminosugars, Carbohydrates, Thioureas, Enzyme inhibitors.

Synthesis of 1-Deoxynojirimycin-Trehalamine Fused Compound and Its Related Compounds

1-Deoxynojirimycin-trehalamine fused compound 10 as a mixture together with 11 and its related compound 19 were synthesized.The enzyme inhibitory activities of the mixture (10 and 11), 19 and 20 exhibited IC 50 values of 0.68, 4.2, and 1.5 μg/ml, respectively, toward rat intestinal maltase.