75646-79-6Relevant academic research and scientific papers
3-Aminotropane-3-carboxylic acids. Preparation and properties
Trigo, Gregorio G.,Avendano, Carmen,Santos, Emilia,Christensen, Halvor N.,Handlogten, Mary E.
, p. 2295 - 2300 (2007/10/02)
The two isomers of 3-aminotropane-3-carboxylic acid have been prepared by hydrolysis of the two α- and β-tropane-3-spiro-5'-hydantoins whose configurations were determined by X-ray crystallography and 13C nmr.The pK'a values of these amino acids and the hydrolysis rates of their N-formyl derivatives have been determined to study the influence of the amino group in an axial or equatorial position.The biological transport - inhibitory action of the two tropane amino acids has also been compared.
