756479-07-9Relevant academic research and scientific papers
Development of prostaglandin D2 receptor antagonist: discovery of highly potent antagonists.
Torisu, Kazuhiko,Kobayashi, Kaoru,Iwahashi, Maki,Nakai, Yoshihiko,Onoda, Takahiro,Nagase, Toshihiko,Sugimoto, Isamu,Okada, Yutaka,Matsumoto, Ryoji,Nanbu, Fumio,Ohuchida, Shuichi,Nakai, Hisao,Masaaki Toda
, p. 4685 - 4700 (2007/10/03)
The process of discovery for highly potent prostaglandin D(2) (PGD(2)) receptor antagonists is reported. A series of N-(p-alkoxy)benzoyl-2-methylindole-4-acetic acids were synthesized and identified as a new class of selective PGD(2) receptor antagonists.
