7565-19-7

Usage

Uses

Used in Chemical Synthesis:
N-BENZYL-N-METHYLGUANIDINE is used as a reagent in chemical synthesis for its ability to participate in various chemical reactions, contributing to the formation of new compounds and materials.
Used in Polymer Production:
In the polymer industry, N-BENZYL-N-METHYLGUANIDINE is used as a component in the production of polymers, where it may influence the properties of the final polymer product, such as strength, flexibility, or chemical resistance.
Used in Foam Manufacturing:
N-BENZYL-N-METHYLGUANIDINE is also utilized in the creation of foams, where it can affect the structure and characteristics of the foam, such as its density, porosity, or stability.
Used in Resin and Adhesive Formulation:
N-BENZYL-N-METHYLGUANIDINE is used in the formulation of resins and adhesives, potentially enhancing their bonding properties, durability, or resistance to environmental factors.

InChI:InChI=1/C9H13N3/c1-12(9(10)11)7-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H3,10,11)

Upstream product

• 2986-19-8 carbamimidothioic acid methyl ester 
• 103-67-3 benzyl-methyl-amine 
• 420-04-2 CYANAMID 
• 17356-08-0 thiourea 
• 13426-94-3 N-methylbenzylamine hydrochloride 

Relevant academic research and scientific papers

Amidination of amines under microwave conditions using recyclable polymer-bound 1H-pyrazole-1-carboxamidine

A convenient one-step transformation of primary and secondary amines into the corresponding unprotected guanidines using 4-benzyl-3,5-dimethyl-1H- pyrazole-1-carboxamidine and its polymer-bound variant is described. The scopes and limitations of the method, the microwave-assistance of amidination as well as a recycling protocol are examined. Georg Thieme Verlag Stuttgart.

A new reagent and its polymer-supported variant for the amidination of amines

New reagents for the high yielding amidination of primary and secondary amines are described. By attaching a benzyl substituent to the 3,5-dimethyl-1H-pyrazole-1-carboxamidine ring, a reagent 1 is obtained which allows easy work-up after amidination because of solubility of byproducts in organic solvents. In addition, the polystyrene-bound analogue 2 was prepared which allows amidination of various amines with high purity.

Novel linker for the solid-phase synthesis of guanidines

A novel linker for the generation of alkyl-, acyl- and arylguanidines as an attachment point in solid phase synthesis has been developed. Introduction of a suitably functionalized thiourea to Wang resin via a carbamate linkage, followed by displacement of sulfur with a 1°or 2°amine affords resin bound guanidines suitably protected for further manipulation. Activation of the thiourea with Mukaiyama's reagent allows for the generation of arylguanidines. Mild acid treatment effects deprotection and liberation from the resin to afford guanidines in good yield and high purity.