Welcome to LookChem.com Sign In|Join Free

CAS

  • or

756525-93-6

Post Buying Request

756525-93-6 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

756525-93-6 Usage

Description

alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol), also known as Mal-amido-PEG8-NHS, is a heterobifunctional crosslinker containing a PEG linker with a maleimide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media, while the NHS ester can be used to label primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group reacts with a thiol group to form a covalent bond, enabling the connection of biomolecules with a thiol.

Uses

Used in Bioconjugation:
alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol) is used as a heterobifunctional crosslinker for linking amineto sulfhydryl-containing compounds or biomolecules. The maleimide functional group reacts with sulfhydryls, and the succinimidyl ester group reacts with amines, allowing for the formation of stable covalent bonds between molecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol) is used as a component in drug delivery systems to improve the solubility, stability, and bioavailability of therapeutic agents. The PEG spacer and reactive groups facilitate the attachment of drugs to targeting moieties or other functional groups, enhancing the overall performance of the drug delivery system.
Used in Diagnostics and Imaging:
In the medical diagnostics and imaging fields, alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol) is used as a labeling agent for the conjugation of imaging agents or contrast agents to biomolecules, such as antibodies or peptides. This allows for the specific targeting and visualization of diseased tissues or cells, improving the accuracy and effectiveness of diagnostic procedures.
Used in Research and Development:
In the research and development of new biomaterials, alpha-MaleiMidopropionyl-oMega-succiniMidyl-8(ethylene glycol) is used as a versatile building block for the synthesis of novel bioconjugates, such as peptide-drug conjugates, protein-drug conjugates, and other hybrid systems. The unique combination of reactive groups and hydrophilic spacer allows researchers to explore new avenues in the design and development of advanced biomaterials for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 756525-93-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,5,6,5,2 and 5 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 756525-93:
(8*7)+(7*5)+(6*6)+(5*5)+(4*2)+(3*5)+(2*9)+(1*3)=196
196 % 10 = 6
So 756525-93-6 is a valid CAS Registry Number.

756525-93-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Mal-PEG8-NHS

1.2 Other means of identification

Product number -
Other names α-Maleimidopropionyl-ω-succinimidyl-8(ethylene glycol)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:756525-93-6 SDS

756525-93-6Upstream product

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 756525-93-6