756531-49-4Relevant academic research and scientific papers
Silica supported chromium trioxide: Microwave promoted oxidative ring closure of α-cyano-β-thioenaminones to isothiazoles
Mishra, Manisha,Mahalanabis, Kumar K.
, p. 204 - 206 (2008/02/09)
Silica supported chromium trioxide is found to be an excellent reagent for oxidative ring closure of α-cyano-β-thioenaminones to isothiazoles in dichloromethane at room temperature or in dry media under microwave irradiation.
Synthesis of novel 3,5-disubstituted-4-isothiazolecarbonitriles
Mishra, Manisha,Dutta Chowdhury,Mahalanabis, Kumar K.
, p. 2681 - 2689 (2007/10/03)
α-Cyano-β-enaminones, obtained by regioselective acylation of β-enaminonitriles, were smoothly converted to thiones which on oxidative cyclization afforded 3,5-disubstituted-4-isothiazolecarbonitriles in good to excellent yields.
