75667-94-6 Usage
Uses
Used in Pharmaceutical Industry:
(3-AMINO-1-ADAMANTYL)ACETIC ACID Hydrochloride is used as a building block for the synthesis of pharmaceuticals due to its unique structure and properties. Its adamantane ring provides a rigid and hydrophobic scaffold, which can be beneficial for the development of new drugs with improved stability, selectivity, and bioavailability.
Used in Chemical Industry:
In the chemical industry, (3-AMINO-1-ADAMANTYL)ACETIC ACID Hydrochloride is used as a reagent in the research and development of new organic compounds. Its amino group can be further functionalized, allowing for the creation of a wide range of derivatives with diverse applications.
Used in Drug Development Research:
(3-AMINO-1-ADAMANTYL)ACETIC ACID Hydrochloride is employed as a reagent in the research and development of new drugs and materials. Its unique structure and properties make it a valuable tool for exploring novel chemical spaces and discovering potential therapeutic agents.
Overall, (3-AMINO-1-ADAMANTYL)ACETIC ACID Hydrochloride is a versatile chemical compound with a variety of potential applications in the pharmaceutical and chemical industries, as well as in drug development research. Its stability, solubility, and unique structural features make it an attractive building block for the synthesis of new compounds and the advancement of scientific knowledge.
Check Digit Verification of cas no
The CAS Registry Mumber 75667-94-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,6,6 and 7 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 75667-94:
(7*7)+(6*5)+(5*6)+(4*6)+(3*7)+(2*9)+(1*4)=176
176 % 10 = 6
So 75667-94-6 is a valid CAS Registry Number.
InChI:InChI=1S/C12H19NO2.ClH/c13-12-4-8-1-9(5-12)3-11(2-8,7-12)6-10(14)15;/h8-9H,1-7,13H2,(H,14,15);1H
75667-94-6Relevant academic research and scientific papers
Tumor-cell-targeted methionine-enkephalin analogues containing unnatural amino acids: Design, synthesis, and in vitro antitumor activity
Horvat, ?tefica,Mlinari?-Majerski, Kata,Glava?-Obrovac, Ljubica,Jakas, Andreja,Veljkovi?, Jelena,Marczi, Sa?ka,Kragol, Goran,Ro??i?, Maja,Matkovi?, Marija,Milosti?-Srb, Andrea
, p. 3136 - 3142 (2007/10/03)
A series of new peptides (8-25) containing different unnatural amino acids of the adamantane type (1-6), was synthesized. Possible cytotoxic activity on human cervical adenocarcinoma (HeLa), larynx carcinoma (HEp-2), colon carcinomas (HT-29, Caco-2), poorly differentiated cells from lymph node metastasis of colon carcinoma (SW-620), mammary gland adenocarcinoma (MCF-7), and melanoma (HBL) cells were tested by the MTT assay. The results were compared with the effect of methionine-enkephalin (Tyr-Gly-Gly-Phe-Met, or opioid growth factor, OGF), and its shorter N-terminal fragments. Peptide analogues containing Cαα-dialkylated glycine (Aaa1, 1) or Cα-alkylated glycine (Aaa2, 2) amino acid residues showed antitumor activity against melanoma, larynx carcinoma, colon carcinomas, and colon metastasis cell lines in vitro. The pentapeptide Tyr-(R,S)-Aaa2-Gly-Phe-Met (18) was the most effective analogue especially against the most antitumor drug-resistant cell lines HEp-2 and SW-620. Apoptosis as a mode of cell death was confirmed in these tumor cells after exposure to pentapeptide 18.
SYNTHESIS AND CHEMICAL TRANSFORMATIONS OF ACETYLAMINO DERIVATIVES OF ADAMANTANE
Novikov, S. S.,Khardin, A. P.,Butenko, L. N.,Kulev, I. A.,Novakov, I. A.,et al.
, p. 1231 - 1232 (2007/10/02)
The synthesis of acetylamino derivatives of adamantane by the Ritter reaction in a mixture of sulfuric and nitric acids is described.Their hydrolysis in the presence of hydrochloric acid was investigated.
