75684-29-6Relevant academic research and scientific papers
An efficient glucose-based ligand for Heck and Suzuki coupling reactions in aqueous media
Bagherzadeh, Mojtaba,Amini, Mojtaba,Derakhshandeh, Parviz Gohari,Haghdoost, Mohammad Mehdi
, p. 441 - 446 (2014)
The glucose-based ligand, N-salicylidene-d-glucosamine (Sal-d-glsmN), was readily obtained by reaction of salicylaldehyde (Hsal) with the d-glucosamine hydrochloride. Ligand Sal-d-glsmN was found to be an efficient ligand in the palladium-catalyzed Suzuki and Heck C-C coupling reactions in aqueous medium under aerobic condition. It was found that the use of Sal-d-glsmN/Pd(OAc) 2 system as a catalyst, aryl halides undergo Suzuki and Heck cross-couplings, respectively, with arylboronic acids and olefins to give the desired products in moderate to excellent yields.
