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H-LEU-ARG-PRO-GLY-NH2 2HCL, also known as Leuprorelin, is a synthetic hormone analog that functions as a potent agonist of gonadotropin-releasing hormone (GnRH). It is utilized in the medical field for the treatment of hormone-related conditions such as prostate cancer, breast cancer, and endometriosis. Leuprorelin works by suppressing the production of hormones that can fuel the growth of these cancers and the symptoms of endometriosis, making it a valuable component in comprehensive treatment plans.

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  • 75690-75-4 Structure
  • Basic information

    1. Product Name: H-LEU-ARG-PRO-GLY-NH2 2HCL
    2. Synonyms: LUTEINIZING HORMONE RELEASING HORMONE FRAGMENT 7-10 DIHYDROCHLORIDE;luteinizing hormone releasing hormone*fragment 7-;LUTEINIZING HORMONE RELEASING HORMONE*FR AGMENT 7-10;H-Leu-Arg-Pro-Gly-NH2HCl;LHRH 7-10 SEQUENCE;Leu-Arg-Pro-Gly-NH2, LH-RH Fragment7-10 dihydrochloride;2-(1-((S)-1-((S)-2-((S)-2-amino-4-methylpentanamido)-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)hydrazinyl)acetic acid dihydrochloride;LH-RH Fragment 7-10 dihydrochloride
    3. CAS NO:75690-75-4
    4. Molecular Formula: C19H38Cl2N8O4
    5. Molecular Weight: 513.46
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 75690-75-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /lyophilized powder
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: H-LEU-ARG-PRO-GLY-NH2 2HCL(CAS DataBase Reference)
    10. NIST Chemistry Reference: H-LEU-ARG-PRO-GLY-NH2 2HCL(75690-75-4)
    11. EPA Substance Registry System: H-LEU-ARG-PRO-GLY-NH2 2HCL(75690-75-4)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: 60
    3. Safety Statements: 53-22-36/37/39-45
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 75690-75-4(Hazardous Substances Data)

75690-75-4 Usage

Uses

Used in Oncology:
Leuprorelin is used as a hormone therapy agent for the treatment of hormone-sensitive cancers such as prostate and breast cancer. It is employed to suppress the production of hormones that contribute to the growth of these cancers, thereby helping to control tumor progression and improve patient outcomes.
Used in Gynecology:
In the field of gynecology, Leuprorelin is used as a treatment for endometriosis, a condition where tissue similar to the lining of the uterus grows outside the uterus. It helps to alleviate the symptoms of endometriosis by reducing the levels of hormones that cause the growth of endometrial tissue.
Used in Combination Therapy:
Leuprorelin is often used in combination with other medications as part of a comprehensive treatment plan for various hormone-related conditions. This approach allows for a more effective management of symptoms and disease progression, enhancing the overall therapeutic outcomes for patients.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Leuprorelin is utilized as an active pharmaceutical ingredient in the formulation of various drug products. It is typically administered as a subcutaneous injection, providing a controlled release of the hormone analog to ensure optimal therapeutic effects.
Overall, H-LEU-ARG-PRO-GLY-NH2 2HCL, or Leuprorelin, plays a significant role in the management of hormone-related medical conditions, offering a targeted approach to treatment that can improve patient outcomes and quality of life.

Check Digit Verification of cas no

The CAS Registry Mumber 75690-75-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,6,9 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 75690-75:
(7*7)+(6*5)+(5*6)+(4*9)+(3*0)+(2*7)+(1*5)=164
164 % 10 = 4
So 75690-75-4 is a valid CAS Registry Number.

75690-75-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[2-[(2-amino-4-methylpentanoyl)amino]-5-(diaminomethylideneamino)pentanoyl]-N-(2-amino-2-oxoethyl)pyrrolidine-2-carboxamide,hydrochloride

1.2 Other means of identification

Product number -
Other names LH-RH Fragment 7-10 dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:75690-75-4 SDS

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