75700-19-5Relevant academic research and scientific papers
Formation of meta-arylsulfanyl- and meta-(alkylsulfanyl)phenols from cyclohexane-1,3-diones
Do Van Thanh, Nhan,Patra, Subrata,Clive, Derrick L.J.
, p. 4343 - 4350 (2018/07/13)
Reaction of cyclohexane-1,3-diones with TsCl/Et3N and treatment of the resulting 3-(tosyloxy)cyclohex-2-en-1-ones with aryl- or alkyl thiols and K2CO3 in MeCN gives 3-(arylsulfanyl)cyclohex-2-en-1-ones or 3-(alkylsulfanyl)cyclohex-2-en-1-ones, respectively. These compounds are easily brominated at C-2 by using NBS in MeCN; exposure to DBU in MeCN at room temperature then causes aromatization to afford meta-arylsulfanyl- and meta-(alkylsulfanyl)phenols.
An efficient FeCl3-catalyzed condensation of thiols with 1,3-dicarbonyl compounds under solvent-free conditions
Kumari, Kumkum,Singh, Krishna Nand
, p. 213 - 216 (2014/02/14)
A practical and environmentally friendly method has been developed for the synthesis of thiol-substituted cyclohex-2-enones using a FeCl 3-catalyzed condensation of cyclic 1,3-dicarbonyl compounds and aromatic/aliphatic thiols under solvent-fre
