75708-29-1 Usage
Originator
Adimolol
hydrochloride
,ZYF Pharm
Chemical
Manufacturing Process
A mixture consisting of 3 g of 1-(3-amino-3,3-dimethyl-n-propyl)
benzimidazolidinone-2, 3.3 g of 1-[naphthyl-(1)-oxyl]propylene-(2,3)-epoxide
and 12 ml of 98% ethanol were refluxed for three hours. Thereafter, the
ethanol was distilled off, the residue was taken up in some methanol, and the
solution was acidified with 1 N hydrochloric acid and then extracted with ethyl
acetate. The ethyl acetate was distilled out of the extract solution, and ether
and some water were added to the residue, whereupon a crystalline substance
separated out. The product was recrystallized from ethanol, yielding 60% of
theory of ()-1-(3-((2-hydroxy-3-(1-naphthyloxy)propyl)amino)-3-
methylbutyl)-2-benzimidazolinone, which had a melting point of 161°C.
In practice it is usually used as hydrochloride.
Therapeutic Function
Alpa- and Beta-adrenergic blocker
Check Digit Verification of cas no
The CAS Registry Mumber 75708-29-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,0 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 75708-29:
(7*7)+(6*5)+(5*7)+(4*0)+(3*8)+(2*2)+(1*9)=151
151 % 10 = 1
So 75708-29-1 is a valid CAS Registry Number.
InChI:InChI=1/C25H29N3O3.ClH.H2O/c1-25(2,14-15-28-22-12-6-5-11-21(22)27-24(28)30)26-16-19(29)17-31-23-13-7-9-18-8-3-4-10-20(18)23;;/h3-13,19,26,29H,14-17H2,1-2H3,(H,27,30);1H;1H2
