75712-61-7

Upstream product

• 18929-82-3 4,6-O-benzylidene-α-D-glucopyranosyl-(1→1)-4',6'-O-benzylidene-α-D-glucopyranoside 
• 112-67-4 n-hexadecanoyl chloride 
• 57-10-3 1-hexadecylcarboxylic acid 

Downstream Products

• 130150-96-8 4,6:4',6'-di-O-benzylidene-3-O-palmitoyl-2',3'-O-(tetraisopropyldisiloxane-1,3-diyl)-α,α-trehalose 
• 147347-44-2 4,6:4',6'-di-O-benzylidene-2-O-palmitoyl-2',3'-O-(tetraisopropyldisiloxane-1,3-diyl)-α,α-trehalose 
• 147347-57-7 4,6:4',6'-di-O-benzylidene-2'-O-bromoacetyl-2-O-palmitoyl-3,3'-di-O-stearoyl-α,α-trehalose 
• 147347-56-6 4,6:4',6'-di-O-benzylidene-2'-O-bromoacetyl-2-O-palmitoyl-α,α-trehalose 
• 75712-62-8 Hexadecanoic acid (4aR,6R,7R,8S,8aR)-8-acetoxy-6-((4aR,6R,7R,8S,8aR)-7,8-diacetoxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yloxy)-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl ester 

Relevant academic research and scientific papers

Synthesis of diacylated trehalose sulfates: Candidates for a tuberculosis vaccine

Able antigen analogues: Analogues of the mycobacterial sulfoglycolipid antigen 1 isolated from Mycobacterium tuberculosis have been prepared by a short and general route. Some derivatives showed interesting immunogenic properties and activated cytotoxic T

Synthesis of α,α-trehalose 2,3- and 2,3'-diesters with palmitic and stearic acid: Potential immunoreactants for the serodiagnosis of tuberculosis

Regioselective monoacylation, by the stannylation method, of 4,6 : 4',6'-di-O-benzylidene-α,α-trehalose with palmitoyl or stearoyl chloride afforded the 2-palmitate and 2-stearate of the diacetal, whereas partial diacylation led to the corresponding 2,3'-

'Le BOP' Reagent and Imidazole for Selective O-Acylation of Trehalose

Benzotriazolyl-N-oxytris(dimethylamino)phosphonium hexafluorophosphate ('Le BOP' reagent) in combination with imidazole provides a very mild system for selective esterification of polyhydroxy-compounds.An example is given showing an improved selectivity towards position 2 of trehalose, leading to new derivatives of 'Cord-Factor'.