757188-72-0

Upstream product

• 757189-24-5 4'-(3-benzyloxy-4-methoxyphenyl)-2'-(pyrrolidin-1-ylcarbonyl)-1'H-1,3'-bipyrrole 
• 757189-06-3 methyl 4'-(3-benzyloxy-4-methoxyphenyl)-1'H-1,3'-bipyrrole-2'-carboxylate 
• 757188-89-9 tert-butyl 4'-(3-benzyloxy-4-methoxyphenyl)-2'-(pyrrolidin-1-ylcarbonyl)-1'H-1,3'-bipyrrole-1'H-carboxylate 

Downstream Products

• 757189-12-1 acetic acid 2-methoxy-5-(7-oxo-1,7-dihydro-1,3b-diaza-cyclopenta[a]pentalen-3-yl)-phenyl ester 
• 918331-21-2 3-(3-benzyloxy-4-methoxyphenyl)-1-(methylsulfonyl)pyrrolo[2,3-b]pyrrolizin-8(1H)-one 

Relevant academic research and scientific papers

Synthesis of new dipyrrolo- and furopyrrolopyrazinones related to tripentones and their biological evaluation as potential kinases (CDKs1-5, GSK-3) inhibitors

We herein describe the synthesis of novel dipyrrolo- and furopyrrolopyrazinones related to highly cytotoxic tripentones and to their oximes. The synthetic pathway involved in particular a Curtius rearrangement and a subsequent cyclisation into the title p

Synthesis and biological evaluation of novel pyrrolopyrrolizinones as anticancer agents

We herein describe the synthesis of novel 3-(het)aryl-pyrrolo[2,3-b]pyrrolizin-8(1H)-ones starting from commercial (het)aryl-acetonitriles. A more convergent route was also described through the first synthesis of ethyl 3-amino-4-bromo-1H-pyrrole-2-carbox

First synthesis of arylpyrrolo- and pyrazolopyrrolizinones as useful agents with potential biological interest

Novel arylpyrrolo- and pyrazolopyrrolizinones were prepared in three or four steps starting from aminoarylpyrrole and pyrazole carboxylates through the cyclisation of a Vilsmeier-Haack intermediate. This synthesis was enhanced by diverse N-protections of