757189-11-0

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 1699-39-4 2-(3-(benzyloxy)-4-methoxyphenyl)acetonitrile 

Downstream Products

• 757189-08-5 ethyl 3-(3-benzyloxy-4-methoxyphenyl)-4-(1H-pyrrol-1-yl)-1H-pyrazole-5-carboxylate 
• 757189-18-7 5-(3-benzyloxy-4-methoxyphenyl)-1-benzyl-5-(pyrrolidin-1-ylcarbonyl)-4-(1H-pyrrol-1-yl)-1H-pyrazole 
• 757189-19-8 3-(3-benzyloxy-4-methoxyphenyl)-1-benzyl-5-(pyrrolidin-1-ylcarbonyl)-4-(1H-pyrrol-1-yl)-1H-pyrazole 
• 757188-97-9 3-(3-(benzyloxy-4-methoxyphenyl)-5-pyrrolidin-ylcarbonyl)-4-(1H-pyrrol-1-yl)-1H-pyrazole 
• 757189-21-2 3-(3-benzyloxy-4-methoxyphenyl)-1-benzylpyrazolo[3,4-b]pyrrolizin-8(1H)-one 
• 757189-20-1 3-(3-benzyloxy-4-methoxyphenyl)-2-benzylpyrazolo[3,4-b]pyrrolizin-8(1H)-one 
• 916735-61-0 3-(3-benzyloxy-4-methoxyphenyl)-2-methylpyrazolo[3,4-b]pyrrolizin-8(1H)-one 
• 916735-60-9 3-(3-benzyloxy-4-methoxyphenyl)-1-methylpyrazolo[3,4-b]pyrrolizin-8(1H)-one 
• 916735-59-6 5-(3-benzyloxy-4-methoxyphenyl)-1-methyl-3-(pyrrolidin-1-ylcarbonyl)-4-(1H-pyrrol-1-yl)-1H-pyrazole 
• 916735-58-5 3-(3-benzyloxy-4-methoxyphenyl)-1-methyl-5-(pyrrolidin-1-ylcarbonyl)-4-(1H-pyrrol-1-yl)-1H-pyrazole 

Relevant academic research and scientific papers

Synthesis of novel pyrazolopyrrolizinones as prospective anticancer agents

Herein we describe the access of novel pyrazolopyrrolizinones from commercial arylacetonitriles. The first step conducts to the corresponding aminoester which was first submitted to Clauson-Kaas procedure. Amidification and cyclisation afford then the fir