757235-52-2

Upstream product

• 110-89-4 piperidine 
• 61380-86-7 6-(4-methoxyphenyl)-3-cyano-4-methylsulfanyl-2H-pyran-2-one 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 1194451-28-9 (E)-3-(2-(4-methoxyphenyl)-5,6-dihydro-4H-benzo[kl]acridin-3-yl)-3-(piperidin-1-yl)acrylonitrile 
• 1236223-60-1 6'-(4-methoxyphenyl)-2'-phenyl-3,4,5,6-tetrahydro-2H-[1,4]bipyridinyl-3-carbonitrile 
• 1190359-63-7 4-(4-Methoxy-phenyl)-2-piperidin-1-yl-9H-fluorene-1-carbonitrile 
• 1434247-39-8 1-(4-methoxyphenyl)-3-(piperidin-1-yl)-5H-dibenzo[d,f][1,3]diazepin-6(7H)-one 
• 1214891-17-4 2-cyano-5-(4-methoxyphenyl)-5-oxo-3-piperidin-1-yl-pent-2-enoic acid ethyl ester 
• 1632038-87-9 4'-methoxy-3-(2-methyl-1,8-naphthyridin-3-yl)-5-(piperidin-1-yl)biphenyl-4-carbonitrile 
• 1632038-92-6 4-(4-methoxyphenyl)-2-(piperidin-1-yl)-5,6-dihydronaphtho[2,1-b][1,8]naphthyridine-1-carbonitrile 

Relevant academic research and scientific papers

Ultrasound-assisted synthesis, photophysical behaviour and single crystal X-ray analysis of highly functionalized prenylarenes

A rapid, ultrasound assisted base-catalysed metal free synthesis of a novel series linear prenylarenes 17 incorporated with donor-acceptor functionalities is described via carbanion-induced ring transformation of 4-amino-6-aryl-3-cyano-2H-pyran-2-ones 15 with 6-methylhept-5-en-2-one 16 at room temperature with high yields. Notably, all of the synthesised prenylarenes exhibited blue fluorescence in the 406–468 nm region. The stokes shift, optical band gap, and quantum yield of compounds 17a-17l were computed using their absorption and emission spectra. A significant positive solvatochromic effect was observed, and concentration studies revealed the non-aggregating behaviour of synthesised prenylarenes. Single crystal X-ray diffraction analysis of 17d revealed that crystal belongs to triclinic system with P-1 space group with twisted phenyl rings.

Transition metal-free synthesis of sterically hindered allylarenes from 5-hexene-2-one

A simple, efficient and transition metal-free strategy was established for the synthesis of highly functionalized, sterically hindered allylarenes (6, 7 & 8) by base-mediated ring transformation of 2-oxo-6-aryl-4-(methylthio/sec-amino)-2H-pyran-3-carbonit

First Dual Responsive “Turn-On” and “Ratiometric” AIEgen Probe for Selective Detection of Hydrazine Both in Solution and the Vapour Phase

A new dual responsive “turn-on” and “ratiometric” aggregation-induced emission luminogen (AIEgen) 3-formyl-5-(piperidin-1-yl)biphenyl-4-carbonitrile 6 a (FPBC 6 a) for selective detection of hydrazine in solution as well as in vapour phase is described. A

Base-promoted regioselective synthesis of 1,2,3,4-terahydroquinolines and quinolines from N-boc-3-piperidone

An efficient synthesis of 1,2,3,4-tetrahydroquinolines with donor and acceptor group has been delineated by base mediated ring transformation of 6-aryl-4-substituted-2H-pyran-2-one-3-carbonitriles by N-boc-3-piperidone followed by consecutive deprotection

White light induced E/Z-photoisomerization of diphenylamine-tethered fluorescent stilbene derivatives: Synthesis, photophysical, and electrochemical investigation

A facile synthesis and detailed photophysical investigation of E/Z-isomerization of fluorescent diphenylamine tethered stilbene derivatives (DPASs) under white light exposure have been carried out to understand the effect on fluorescence, electrochemical

Chemoselective synthesis of isolated and fused fluorenones and their photophysical and antiviral properties

Highly functionalized fluorenones were synthesized by an intramolecular cyclization of 2′′-halo-[1,1′:3′,1′′-terphenyl]-4′-carbonitriles in the presence of n-butyllithium or lithium aluminium hydride. The precursor was synthesized by ring transformation o

A Metal-Free Approach for the Synthesis of 2-Tetralones via Carbanion-Induced Ring Transformation of 2 H -Pyran-2-ones

A metal-free, ultrasound-assisted approach for the synthesis of highly functionalized 2-tetralones in high yields is described. The process involves ring transformation of 2 H -pyran-2-ones with the spirocyclic ketone 1,4-cyclohexandione monoethylene keta

A dual colorimetric-ratiometric fluorescent probe NAP-3 for selective detection and imaging of endogenous labile iron(III) pools in C. elegans

The discovery of an iron(III)-selective ratiometric fluorescent probe to detect and visualize endogenous labile iron pools in living organisms at the molecular level has been long awaited. Herein we report the first dual colorimetric and ratiometric fluor

Base mediated regioselective synthesis of highly functionalized conjugated enones

A simple, regioselective, convenient, and base mediated synthesis of (2E,4E)-5-aryl-6-oxo-6-phenyl-3-sec.amino-hexa-2,4-dienenitriles has been achieved by the reaction of 6-aryl-4-sec.amino-2-oxo-2H-pyran-3-carbonitriles and benzyl cyanide. This reaction

New convenient synthesis of fluorescent 1,8-naphthyridines and the metal-sensing properties of the dyes

A new and efficient approach to a series of highly fluorescent non-aggregating donor-acceptor 1,8-naphthyridines is described. Examination of the photophysical properties of the 1,8-naphthyridines revealed that the presence of donor-acceptor functionality