75727-47-8 Usage
Uses
Used in Pharmaceutical Development:
5-(4-METHYL-PIPERAZIN-1-YL)-5-OXO-PENTANOIC ACID is used as a pharmaceutical intermediate for its potential biological activity. 5-(4-METHYL-PIPERAZIN-1-YL)-5-OXO-PENTANOIC ACID's unique structure and properties make it a valuable component in the development of new drugs, targeting various therapeutic areas.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 5-(4-METHYL-PIPERAZIN-1-YL)-5-OXO-PENTANOIC ACID serves as a key building block for the synthesis of novel compounds with potential therapeutic applications. Its versatile chemical structure allows for the design and optimization of new molecules with improved pharmacological properties.
Used in Drug Synthesis:
5-(4-METHYL-PIPERAZIN-1-YL)-5-OXO-PENTANOIC ACID is utilized as a key synthetic precursor in the production of various pharmaceuticals. Its unique functional groups and structural features enable the creation of diverse drug candidates with potential applications in treating a wide range of diseases and conditions.
Used in Drug Formulation:
In the pharmaceutical industry, 5-(4-METHYL-PIPERAZIN-1-YL)-5-OXO-PENTANOIC ACID may be employed as an excipient or an active pharmaceutical ingredient in drug formulations. Its properties can contribute to the stability, solubility, and bioavailability of the final drug product, ensuring optimal therapeutic efficacy and safety.
Used in Drug Delivery Systems:
5-(4-METHYL-PIPERAZIN-1-YL)-5-OXO-PENTANOIC ACID can be incorporated into drug delivery systems to enhance the pharmacokinetics and pharmacodynamics of therapeutic agents. Its potential to improve drug release profiles, target specific tissues, and reduce side effects makes it a valuable component in the development of advanced drug delivery technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 75727-47-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,2 and 7 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 75727-47:
(7*7)+(6*5)+(5*7)+(4*2)+(3*7)+(2*4)+(1*7)=158
158 % 10 = 8
So 75727-47-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H18N2O3/c1-11-5-7-12(8-6-11)9(13)3-2-4-10(14)15/h2-8H2,1H3,(H,14,15)
75727-47-8Relevant academic research and scientific papers
Streptogramin derivatives, their preparation and compositions containing them
-
, (2008/06/13)
Group A streptogramin derivatives of general formula (I) in which:R1 represents a halogen atom or an azido or thiocyanato radical,R2 represents a hydrogen atom or a methyl or ethyl radical,R3 represents a hydrogen atom, or the residue of an aliphatic, cycloaliphatic, aromatic, araliphatic, heterocyclic or heterocyclylaliphatic ester which may be substituted, andthe bond - - -represents a single bond (stereochemistry 27R) or a double bond,as well as its salts when they exist.
Polycyclic aromatic compounds as anticancer agents: Structure-activity relationships of chrysene and pyrene derivatives
Banik, Bimal K,Becker, Frederick F
, p. 593 - 605 (2007/10/03)
A large number of diamides and diamines were synthesized using 6-amino chrysene and 1-amino pyrene as starting materials. A structure-activity study with cis-platinum as internal control against animal and human tumor lines was carried out in vitro. This study indicated that the in vitro cytotoxicity toward these lines depends on the functionality present in the molecules. The diamino compounds were found to be more potent than the diamides, and these were equally active irrespective of the end heterocyclic group whereas the activity of the diamides was strongly dependent on the terminal unit. In general, the diamides containing chrysene as the chromophore were more active than those with a pyrene ring. The size of the end heterocyclic ring, along with the nature of the spacer connecting the polycyclic ring to the heterocyclic ring, seemed to affect the biological activity in certain stabilizing agens. This agent also demonstrated the stabilizing agents. This agent also demonstrated the capacity to produce differentiation in leukemia cells lines.
