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Marcfortine A is an indole alkaloid originally isolated from P. roqueforti, a fungus found in soil and decaying organic matter. It exhibits potent nematocidal activity against parasitic nematodes, particularly H. contortus, and has the ability to inhibit motility of adult worms. Its mode of action is thought to involve blocking cholinergic neuromuscular transmission.
Used in Veterinary Medicine:
Marcfortine A is used as a nematocide for the treatment of parasitic nematode infections in animals. It is effective against various species of nematodes, including H. contortus, T. colubriformis, and O. ostertagi, and has demonstrated dose-dependent inhibition of nicotine-induced calcium mobilization in cells expressing human nicotinic acetylcholine receptors (nAChRs) and muscle-type nAChRs.
Used in Pharmaceutical Research:
Marcfortine A is used as a research compound for studying the effects of cholinergic neuromuscular transmission blockade on parasitic nematodes. Its structural relationship to paraherquamides and potent nematocidal activity make it a valuable tool for investigating novel approaches to combat parasitic infections.

75731-43-0

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75731-43-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 75731-43-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,3 and 1 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 75731-43:
(7*7)+(6*5)+(5*7)+(4*3)+(3*1)+(2*4)+(1*3)=140
140 % 10 = 0
So 75731-43-0 is a valid CAS Registry Number.

75731-43-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name Marcfortine A

1.2 Other means of identification

Product number -
Other names From Penicillium roqueforti

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:75731-43-0 SDS

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