75732-49-9 Usage
Description
1-(2,2-dioxido-1,2-oxathiolan-3-yl)cyclohexanol, also known as carbovir, is a synthetic chemical compound with potent antiviral properties. It is characterized by its unique oxathiolane ring and cyclohexanol group, which contribute to its ability to interfere with the replication of viral DNA by inhibiting the reverse transcriptase enzyme.
Uses
Used in Pharmaceutical Industry:
1-(2,2-dioxido-1,2-oxathiolan-3-yl)cyclohexanol is used as a nucleoside reverse transcriptase inhibitor for the treatment of viral infections, particularly HIV and hepatitis B. Its antiviral action is attributed to its ability to inhibit the reverse transcriptase enzyme, which is crucial for the replication of the virus. By blocking this enzyme, carbovir prevents the virus from multiplying and infecting new cells, thus helping to control and manage the progression of these viral infections.
Additionally, the compound's unique chemical structure allows for potential development in other therapeutic areas, such as cancer treatment or other viral diseases, where the inhibition of specific enzymes or proteins is required. However, further research and development are necessary to explore these possibilities.
Check Digit Verification of cas no
The CAS Registry Mumber 75732-49-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,3 and 2 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 75732-49:
(7*7)+(6*5)+(5*7)+(4*3)+(3*2)+(2*4)+(1*9)=149
149 % 10 = 9
So 75732-49-9 is a valid CAS Registry Number.
75732-49-9Relevant articles and documents
Lithium aluminum hydride-aluminum hydride reduction of sultones
Smith, Michael B.,Wolinsky, Joseph
, p. 101 - 106 (2007/10/02)
Lithium aluminum hydride-aluminum hydride reduction of secondary and tertiary (C-O) substituted γ-sultones or α-alkyl-β'-hydroxy γ-sultones yields mercapto alcohols and mercapto diols, respectively, in fair to good yield.These products result from S-O cleavage of the sultone ring.Primary sultones and α-dialkyl-β'-hydroxy γ-sultones give predominantly C-O cleavage to form sulfonic acid derivatives. β-Sultones are much less reactive toward the mixed hydride, and refluxing in dioxane is required for their reduction.
