75737-21-2

Upstream product

• 502-49-8 cycloactanone 
• 75737-04-1 4-(4-Chloro-phenyl)-3,4,5,6,7,8,9,10-octahydro-1H-cyclooctapyrimidine-2-thione 
• 75736-99-1 2-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-cyclooctanone 
• 104-88-1 4-chlorobenzaldehyde 
• 79-11-8 chloroacetic acid 
• 75737-09-6 2-Acetyl-4-(4-chloro-phenyl)-5,6,7,8,9,10-hexahydro-4H-1-thia-3a,11-diaza-cycloocta[f]inden-3-one 

Relevant academic research and scientific papers

Reactions with (Arylmethylene)cycloalkanones. 4. Synthesis of Derivatives of Octahydrocyclooctathiazolopyrimidin-3-one of Expected Biological Activity

Cyclooctapyrimidin-2-thiones (III) were prepared by heating 2-(arylmethylene)cyclooctanones with thiourea in ethanolic potassium hydroxide.Compounds III reacted with chloroacetic acid to yield 2-acetyl-2,3,6,7,8,9,10,11-octahydro-5H-cyclooctathiazolopyrimidin-3-ones (IV).The 2-arylmethylene derivatives (V) and the 2-arylhydrazono derivatives VI were prepared.