75751-72-3 Usage
Uses
Used in Pharmaceutical Industry:
2-Azaspiro[4.4]nonan-3-one is used as a key intermediate in the synthesis of drugs such as atropine, scopolamine, and cocaine. Its unique structure and reactivity make it an essential building block for the development of new medications.
Used in Therapeutic Applications:
2-Azaspiro[4.4]nonan-3-one is used as an anticonvulsant agent for the treatment of seizure disorders. Its ability to modulate neuronal activity and reduce seizure frequency makes it a promising candidate for further research and development in the field of neurology.
Additionally, it is used as an anticancer agent due to its potential to inhibit the growth of certain cancer cells. Its mechanism of action and selectivity towards cancer cells warrant further investigation for its application in oncology.
Used in Organic Synthesis:
2-Azaspiro[4.4]nonan-3-one is used as a catalyst in various organic synthesis processes. Its unique structural features and reactivity enable it to facilitate and enhance the efficiency of chemical reactions, making it a valuable tool in the field of organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 75751-72-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,5 and 1 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 75751-72:
(7*7)+(6*5)+(5*7)+(4*5)+(3*1)+(2*7)+(1*2)=153
153 % 10 = 3
So 75751-72-3 is a valid CAS Registry Number.
InChI:InChI=1/C8H13NO/c10-7-5-8(6-9-7)3-1-2-4-8/h1-6H2,(H,9,10)
75751-72-3Relevant academic research and scientific papers
Understanding the conformational analysis of gababutin based hybrid peptides
Konda, Maruthi,Jadhav, Rohit G.,Maiti, Sayan,Mobin, Shaikh M.,Kauffmann, Brice,Das, Apurba K.
supporting information, p. 1728 - 1735 (2018/03/21)
Constrained γ-amino acid gababutin (Gbn) based peptides that form different conformations have been synthesized. Striving to rationalize the impact of side chain orientations framing tetrapeptide-based supramolecular organic frameworks and morphological entities, Gbn incorporated hybrid peptides Boc-Gbn-Aib-Aaa-Aib-OMe (where Aaa = Phe(F) for peptide 1, Leu(L) for peptide 2 and Tyr(Y) for peptide 3) were synthesized by changing the amino acid at the third position. The solution state dual folded conformation (C12/C10 H-bonded) is probed by 2D NMR spectroscopy in support of a DMSO-d6 titration and VT NMR experiments. Peptides 1-3 adopt a C12/C10 type H-bonded dual folded conformation in the crystal state. In addition, distinct supramolecular frameworks result from the modification and orientation of the third residue side chain of peptides 1-3. A solvent induced morphological diversity of peptides 1-3 is attained by modifying the side chain backbone of the tetrapeptides, which are investigated by various microscopic (SEM and AFM) studies. Gbn-based peptides 1-3 show significant morphological and supramolecular packing properties, which are fairly different from those of their gabapentin (Gpn) based analogue peptides.
