75776-08-8 Usage
Uses
Used in Medicinal Chemistry:
1-(2-Chloroethyl)-3-[10-methylthio-9-oxo-1,2,3-trimethoxy-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]urea is used as a potential candidate in medicinal chemistry for its unique structural features. Its complex molecular composition may allow for specific interactions with biological targets, making it a valuable compound for the development of new drugs or therapies.
Used in Organic Synthesis Research:
In the field of organic synthesis, 1-(2-Chloroethyl)-3-[10-methylthio-9-oxo-1,2,3-trimethoxy-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]urea serves as a research tool. Its intricate structure can be utilized to study various synthetic pathways and reaction mechanisms, contributing to the advancement of chemical knowledge and the development of novel synthetic methods.
Check Digit Verification of cas no
The CAS Registry Mumber 75776-08-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,7 and 6 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 75776-08:
(7*7)+(6*5)+(5*7)+(4*7)+(3*6)+(2*0)+(1*8)=168
168 % 10 = 8
So 75776-08-8 is a valid CAS Registry Number.
InChI:InChI=1/C23H27ClN2O5S/c1-29-18-11-13-5-7-16(26-23(28)25-10-9-24)15-12-17(27)19(32-4)8-6-14(15)20(13)22(31-3)21(18)30-2/h6,8,11-12,16H,5,7,9-10H2,1-4H3,(H2,25,26,28)/t16-/m0/s1
75776-08-8Relevant academic research and scientific papers
Lin, Tai-Shun,Shiau, George T.,Prusoff, William H.,Harmon, Robert E.
, p. 1440 - 1442 (1980)
A series of urea and nitrosourea analogues of N-deacetylmethylthiocolchicine (1) has been synthesized, and their antineoplastic and antiviral activities were evaluated.The objective for combination of two active moieties, such as thiocolchicine and nitrosourea, into one molecule was the generation of compounds with potential improved biological and pharmacological properties.The ED50 for 2, 3, 4, and 5 was 1.6, 1.2, 3.3, and 1.8*10-8 M for L1210 cells and 3.0, 2.7, 2.9, and 2.6*10-8 M for S-180 cells, respectively.The synthesis and cytotoxic and antiviral properties of these compounds are discussed.
