75784-79-1Relevant academic research and scientific papers
1-HYDROXY-2-AMINOETHANEPHOSPHONIC ACID AND DERIVATIVES
Zygmunt, Jan,Walkowiak, Urszula,Mastalerz, Przemyslaw
, p. 233 - 240 (2007/10/02)
Oxirane ring opening in diethyl 1,2-epoxy-1-methylethanephosphonate with ammonia or amines yields products with OH group at position 1 and amino group at position 2.Structural evidence for 1-hydroxy-1-methyl-2-aminoethanephosphonic acid is provided by its conversion to 2-oxo-propanephosphonic acid upon diazotization.Ammonolysis of diethyl 1,2-epoxyethanephosphonate yields the naturally occurring phosphonic analog of isoserine.
