75794-04-6Relevant articles and documents
3-Hydroxychromones as cyclin-dependent kinase inhibitors: Synthesis and biological evaluation
Lee, Jinho,Park, Taesik,Jeong, Shinwu,Kim, Kyoung-Hee,Hong, Changyong
, p. 1284 - 1287 (2007)
A novel series of 3-hydroxychromones were prepared and found to be CDK inhibitors. Isothiazolidine 1,1-dioxide analogues showed potent CDK1 and CDK2 inhibitory activities and inhibited proliferation of EJ, HCT116, SW620, and MDAMB468 cancer cells.