757961-61-8Relevant academic research and scientific papers
Ruthenium-indenylidene olefin metathesis catalyst with enhanced thermal stability
Kabro, Anzhelika,Roisnel, Thierry,Fischmeister, Cedric,Bruneau, Christian
supporting information; experimental part, p. 12255 - 12261 (2011/02/22)
Two new ruthenium complexes bearing a bidentate (κ2O,C)- isopropoxy-indenylidene ligand and a PPh3 (9) or PCy3 (10, Cy=cyclohexyl) ligand have been synthesized and fully characterized by 1H and 13C NMR spectroscopy and X-ray crystallography. Complex 10 displays a very high thermal stability with a half life of six days at 110°C in [D8]toluene. Complex 10 was evaluated in various ring-closing metathesis reactions and ring-opening metathesis polymerization of dicyclopentadiene, in which it showed a latent behavior with low activity at room temperature and high activity upon thermal activation. Hot catalysts! Two new ruthenium complexes bearing a bidentate (κ2O,C)-isopropoxy- indenylidene ligand and a PPh3 or PCy3 (1, Cy=cyclohexyl; see picture) ligand are thermally stable catalysts. Complex 1 displays a latent behavior in olefin-metathesis transformations and possesses a very high thermal stability with a half life of six days at 110°C in [D8]toluene. This complex features very low activity at room temperature and higher activity upon thermal activation.
Diphenylethylene compounds and uses thereof
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, (2008/06/13)
The present invention relates to Diphenylethylene Compounds and compositions comprising a Diphenylethylene Compound. The present invention also relates to methods for preventing or treating various diseases and disorders by administering to a subject in need thereof one or more Diphenylethylene Compounds. In particular, the invention relates to methods for preventing or treating cancer or an inflammatory disorder by administering to a subject in need thereof one or more Diphenylethylene Compounds. The present invention further relates to articles of manufacture and kits comprising one or more Diphenylethylene Compounds.
