757965-53-0Relevant academic research and scientific papers
Discovery of novel prostaglandin analogs of PGE2 as potent and selective EP2 and EP4 receptor agonists
Xiao, Yufang,Araldi, Gian Luca,Zhao, Zhong,Brugger, Nadia,Karra, Srinivasa,Fischer, David,Palmer, Elizabeth
, p. 4323 - 4327 (2007)
Analogs of PGE2 with introduction of diene groups at the ω-side chain have been synthesized and evaluated for their binding affinity for EP2 and EP4 receptors. An optimized analog (compound 9b) showed high potency and sele
