757967-06-9Relevant academic research and scientific papers
Multi-triggered self-immolative dendritic compounds
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Page/Page column 23; sheet 2, (2010/11/24)
Novel self-immolative dendritic compounds which have a plurality of cleavable trigger units and hence can release a chemical moiety at their focal point upon a multi-triggering mechanism are disclosed. The novel self-immolative dendritic compounds are gated by a molecular logic gate, being either an AND or OR logic gate and hence can be beneficially used in a variety of biological, chemical and physical applications. Processes of preparing, compositions containing and methods utilizing the novel dendritic compounds are further disclosed.
Self-immolative dendrimer biodegradability by multi-enzymatic triggering.
Amir, Roey J,Shabat, Doron
, p. 1614 - 1615 (2007/10/03)
New self-immolative dendritic molecules have been designed and synthesized. The dendrons are built with a multi-enzymatic triggering mechanism, which initiates their biodegradation through a self-immolative chain fragmentation to release a reporter group
