757976-50-4

Basic information

• Product Name: N¹-((1S)-1-{[(4-hydroxyphenyl)amino]methyl}propyl)-N²-(2-oxo-6-phenyl-2H-pyran-4-yl)-L-leucinamide
• Synonyms: N¹-((1S)-1-{[(4-hydroxyphenyl)amino]methyl}propyl)-N²-(2-oxo-6-phenyl-2H-pyran-4-yl)-L-leucinamide
• CAS NO: 757976-50-4
• Molecular Weight: 463.577
• Mol File: 757976-50-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N¹-((1S)-1-{[(4-hydroxyphenyl)amino]methyl}propyl)-N²-(2-oxo-6-phenyl-2H-pyran-4-yl)-L-leucinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N¹-((1S)-1-{[(4-hydroxyphenyl)amino]methyl}propyl)-N²-(2-oxo-6-phenyl-2H-pyran-4-yl)-L-leucinamide(757976-50-4)
• EPA Substance Registry System: N¹-((1S)-1-{[(4-hydroxyphenyl)amino]methyl}propyl)-N²-(2-oxo-6-phenyl-2H-pyran-4-yl)-L-leucinamide(757976-50-4)

Safety Data

• Hazardous Substances Data: 757976-50-4(Hazardous Substances Data)

Upstream product

• 757975-91-0 (S)-4-Methyl-2-(2-oxo-6-phenyl-2H-pyran-4-ylamino)-pentanoic acid {(S)-1-[(4-benzyloxy-phenylamino)-methyl]-propyl}-amide 
• 51388-20-6 4-benzyloxyaniline hydrochloride 
• 5526-38-5 4-hydroxy-6-phenyl-2H-pyran-2-one 
• 757976-20-8 N-(2-oxo-6-phenyl-2H-pyran-4-yl)-L-leucine 
• 706818-02-2 4-bromo-6-phenyl-2H-pyran-2-one 
• 882296-91-5 (1-{[(4-benzyloxy-phenyl)-(2-nitro-benzenesulfonyl)-amino]-methyl}-propyl)-carbamic acid tert-butyl ester 
• 757976-46-8 tert-butyl [(1S)-1-({[4-(benzyloxy)phenyl]amino}methyl)propyl]carbamate 
• 313067-82-2 N-[4-(benzyloxy)phenyl]-2-nitrobenzenesulfonamide 

Relevant articles and documents

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A modification of novel cathepsin K inhibitors I was carried out. The structural design was aimed at reducing the lipophilic character of compounds I for obtaining better pharmacokinetic profiles. This modification afforded several less lipophilic compoun