75820-45-0

Basic information

• Product Name: 2(3H)-Thiazolone, 4-(1,1-dimethylethyl)-
• Synonyms: 2(3H)-Thiazolone, 4-(1,1-dimethylethyl)-;4-tert-Butylthiazol-2(3H)-one, 96%;4-tert-Butyl-2,3-dihydro-1,3-thiazol-2-one
• CAS NO: 75820-45-0
• Molecular Formula: C7H11NOS
• Molecular Weight: 157.24
• Mol File: 75820-45-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 132-137℃
• Appearance: /
• CAS DataBase Reference: 2(3H)-Thiazolone, 4-(1,1-dimethylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Thiazolone, 4-(1,1-dimethylethyl)-(75820-45-0)
• EPA Substance Registry System: 2(3H)-Thiazolone, 4-(1,1-dimethylethyl)-(75820-45-0)

Safety Data

• Hazardous Substances Data: 75820-45-0(Hazardous Substances Data)

Usage

General Description

The chemical 2(3H)-Thiazolone, 4-(1,1-dimethylethyl)- is a thiazolone compound with a tert-butyl group. It is used as a building block in organic synthesis and pharmaceutical research. Thiazolone compounds have been studied for their potential antibacterial and antifungal properties, and they have also been investigated for their potential use in the development of new drugs. The tert-butyl group on this compound provides steric hindrance and can influence its chemical reactivity and biological activity. Overall, this compound has potential applications in the fields of medicinal chemistry and drug discovery.

Upstream product

• 16687-42-6 ammonium thiocarbamate 
• 5469-26-1 1-Bromopinacolon 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 137363-49-6 Thiocarbonic acid S-(3,3-dimethyl-2-oxo-butyl) ester O-methyl ester 

Relevant articles and documents

TETRAZOLINONE COMPOUNDS AND ITS USE

The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein, R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, a C3-C12 cycloalkyl group or an adamantyl group, etc., which each optionally be substituted; R2 represents a hydrogen atom, an C1-C12 alkyl group, or a halogen atom, etc.; R4 and R5 represent independently of each other a hydrogen atom or an C1-C3 alkyl group, etc.; R6, R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, an C1-C12 alkyl group, a C1-C12 haloalkyl group, an C2-C12 alkenyl group, a C3-C12 cycloalkyl group, an C1-C12 alkoxy group or a C1-C12 haloalkoxy group, etc.; X and Y represent independently of each other a sulfur atom or an oxygen atom; Q represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.

The Structures of 4- and 5-Substituted Δ4-Thiazolin-2-ones

In order to establish the structures of compounds described as Δ4-thiazolin-2-ones ten sets of heterocycles (each comprising a 4- or 5-substituted Δ4-thiazolin-2-one, the N-methyl derivative, and the corresponding 2-methoxythiazole) have been examined by i.r., u.v., and 1H and 13C n.m.r. spectrometry.The i.r. results established that in solution the parent compounds exist entirely or predominantly as the 2-oxo-forms.This conclusion is supported by the 1H n.m.r. evidence, but the u.v. and 13C n.m.r. data do not give a clear distinction between the possible 2-oxo- and 2-hydroxy-structures.