75822-47-8

Upstream product

• 75822-38-7 1-(4-chlorophenacyl)isatin 

Downstream Products

• 1026-22-8 (4-chlorophenyl)(1H-indol-2-yl)methanone 
• 83749-68-2 4-(4-Chloro-phenyl)-2,5-dihydro-pyridazino[4,5-b]indol-1-one 
• 83749-79-5 1-Chloro-4-(4-chloro-phenyl)-5H-pyridazino[4,5-b]indole 

Relevant academic research and scientific papers

Rearrangement Of 1-Indole-2,3-Dione To Form 2-Acylindolyl-3-Carboxylic Acid

It has been shown that 1-indole-2,3-diones are recyclized under the influence of sodium alcoholate to form 2-acylindolyl-3-carboxylic acids.A reaction scheme is proposed for this rearrangement.

Syntheses of 1-alkyl-2-acylindoles, 1-alkyl-2-acylindole-3-carboxylic acids, and their esters, in superbasic media

2-Acylindoles and 2-acylindole-3-carboxylic acids are readily alkylated at the nitrogen atom by haloalkanes in a superbasic medium (DMSO + NaOH). For the carboxylic acids, this reaction may proceed either entirely at the nitrogen atom, or at both the the