75824-03-2

Usage

Uses

Used in Agricultural Industry:
ETHYL 5-CHLORO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE is used as a pesticide or herbicide for its ability to inhibit the growth of certain plants and organisms, thereby protecting crops from pests and diseases.
Used as a Chemical Intermediate:
In the chemical industry, ETHYL 5-CHLORO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE may serve as a reagent or intermediate in the synthesis of other organic compounds, contributing to the development of new products and materials.
Safety Precautions:
When handling and using ETHYL 5-CHLORO-3-(METHYLTHIO)-1,2,4-TRIAZINE-6-CARBOXYLATE, it is crucial to take safety precautions due to its potential harmful effects if ingested, inhaled, or exposed to the skin.

InChI:InChI=1S/C7H8ClN3O2S/c1-3-13-6(12)4-5(8)9-7(14-2)11-10-4/h3H2,1-2H3

Upstream product

• 609-09-6 Diethyl ketomalonate 
• 51101-09-8 5-oxo-3-thioxo-2,3,4,5-tetrahydro-[1,2,4]triazine-6-carboxylic acid ethyl ester 
• 31143-85-8 ethyl 3-(methylthio)-5-oxo-4,5-dihydro-1,2,4-triazine-6-carboxylate 
• 31143-85-8 ethoxycarbonyl-6 hydroxy-5 methylmercapto-3 triazine-1,2,4 

Downstream Products

• 75824-08-7 5-[(2-Ethoxycarbonyl-ethyl)-phenyl-amino]-3-methylsulfanyl-[1,2,4]triazine-6-carboxylic acid ethyl ester 
• 96259-44-8 ethyl 5-amino-3-(methylsulfanyl)-1,2,4-triazine-6-carboxylate 
• 96259-43-7 3-(methylthio)-6-phenyl-8-oxo-7,8-dihydropyrimido<4,5-e>-1,2,4-triazine 
• 112080-85-0 5-(Methyl-phenyl-amino)-3-methylsulfanyl-[1,2,4]triazine-6-carboxylic acid ethyl ester 
• 127488-11-3 3-methylthio-8-oxo-6-(2-propoxyphenyl)-7,8-dihydropyrimido[4,5-e][1,2,4]triazine 
• 1429042-03-4 ethyl 5-(1-(ethyl-d5)-1H-indol-4-ylamino)-3-(methylthio)-1,2,4-triazine-6-carboxylate 
• 1429041-88-2 ethyl 5-(benzo[b]thiophen-4-ylamino)-3-((1R,2S)-2-(tert-butoxycarbonylamino)cyclohexylamino)-1,2,4-triazine-6-carboxylate 
• 1429041-90-6 ethyl 3-((1R,2S)-2-(tert-butoxycarbonylamino)cyclohexylamino)-5-(1-methyl-1H-indol-4-ylamino)-1,2,4-triazine-6-carboxylate 
• 1429042-11-4 ethyl 5-(5-cyclopropylpyridin-3-ylamino)-3-(methylthio)-1,2,4-triazine-6-carboxylate 
• 1429042-12-5 ethyl 5-(6-(cyclopropylcarbamoyl)pyridin-3-ylamino)-3-(methylthio)-1,2,4-triazine-6-carboxylate 
• 1429041-96-2 ethyl 3-(methylthio)-5-(1-(ethyl-d5)-1H-indazol-5-ylamino)-1,2,4-triazine-6-carboxylate 

Relevant academic research and scientific papers

1,2,4-TRIAZINE-6-CARBOXAMIDE KINASE INHIBITORS

Provided are triazine compounds for inhibiting of Syk kinase, intermediates used in making such compounds, methods for their preparation, pharmaceutical compositions thereof, methods for inhibiting Syk kinase activity, and methods for treating conditions mediated at least in part by Syk kinase activity.

Pyridotriazines and pyridopyridazines

This invention relates to bicyclic heterocycles that inhibit cyclin-dependent kinase or tyrosine kinase enzymes, or both, and as such are useful to treat cell proliferative disorders such as angiogenesis, atherosclerosis, restenosis, and cancer as well as immunological disorders such as asthma, rheumatoid arthritis, autoimmune diabetes, and graft rejection associated with transplant surgery in mammals.

Pyridotriazines and pyridopyridazines

This invention relates to bicyclic heterocycles that inhibit cyclin-dependent kinase or tyrosine kinase enzymes, or both, and as such are useful to treat cell proliferative disorders such as angiogenesis, atherosclerosis, restenosis, and cancer as well as immunological disorders such as asthma, rheumatoid arthritis, autoimmune diabetes, and graft rejection associated with transplant surgery in mammals.

Method of treating a patient having precancerous lesions with phenyl cycloamino pyrimidinone derivatives

Derivatives of Phenyl Cycloamino Pyrimidinone are useful for the treatment of patients having precancerous lesions. These compounds are also useful to inhibit growth of neoplastic cells.