75835-20-0Relevant academic research and scientific papers
A facile synthesis of α,α′-(EE)-bis(benzylidene)-cycloalkanones and their antitubercular evaluations
Singh, Nimisha,Pandey, Jyoti,Yadav, Amit,Chaturvedi, Vinita,Bhatnagar, Shalini,Gaikwad, Anil N.,Sinha, Sudhir Kumar,Kumar, Awaneet,Shukla,Tripathi, Rama P.
experimental part, p. 1705 - 1709 (2009/05/26)
An economical and facile synthesis of α,α′-(EE)-bis(benzylidene)-cycloalkanones was achieved by the reaction of cycloalkanones with different aromatic aldehydes using ethanolic KOH in good yields. Few of the selected compounds were reduced with NaBH4 to the respective α,α′-(EE)-bis(benzylidene)-cycloalkanols. All these compounds and our earlier synthesized cyclohexyl phenyl methanols were evaluated for their antitubercular, antifungal and antibacterial activities. Several compounds displayed moderate antitubercular activity with MIC = 12.5-1.56 μg/mL. However, none of the compounds displayed any significant antifungal activity.
AROMATIZATION OF ALIPHATIC COMPOUNDS - V. m-DIALKIYL-BENZENES AND 2-BENZYL-NAPHTALENES
Giannangeli, M.,Baiocchi, L.
, p. 1381 - 1384 (2007/10/02)
Same cyclohexadienols, when heated at 220 deg C with PyHCl, gave, through dehydration and isomerisation, the corresponding benzene derivatives.So 2,6-dibenzyliden-cyclohexanols gave m-dibenzyl-benzenes, 2-benzyliden-1-tetralols gave 2-benzyl-naphtalenes a
