75868-85-8Relevant academic research and scientific papers
Chlorination of 3β-hydroxyl-5-Δ steroids with anhydrous ferric chloride
Liu, Feng-Wu,Liu, Hong-Min,Zhang, Yan-Bing,Zhang, Jing-Yu,Tian, Li-Huan
, p. 825 - 830 (2007/10/03)
Treatment of 3β-hydroxyl-5-Δ steroids with anhydrous FeCl 3 in CH2Cl2 afforded reasonable yields of the corresponding alkyl chlorides with a retention of configurations. The structures of the chlorine-exchanging products were determined by NMR and HRMS spectra. The absolute configurations were confirmed by X-ray crystal analysis of 3β-chloro-androst-5-en-17-one. The generality and scope of the reaction were also investigated.
CATALYTIC REARRANGEMENT OF α-D-GLUCOSE 1,2-ORTHOACETATE DERIVATIVES OF PREGNENOLONE AND 16-DEHYDROPREGNENOLONE
Samoshina, N. F.,Denisenko, V. A.,Novikov, V. L.,Uvarova, N. I.
, p. 177 - 182 (2007/10/02)
The rearrangement of pregnenolone and 16-dehydropregnenolone α-D-glucose orthoacetates in the presence of mercuric bromide is, because of the high specific selectivity and satisfactory yields of the desired β-D-glucosides, the most effective method of glycosylating the steroids mentioned.
