75902-76-0 Usage
Structure
Complex structure containing a benzofuran ring and a urea group
Derivative
Derived from 1-methyl-urea
Functional Groups
Methoxy group (–OCH3) at position 4 of the benzofuran ring
Piperidyl ethoxy group (–C5H10N–C2H4O–) attached to the benzofuran ring
Potential Applications
Pharmaceutical research
Biological activity or medicinal properties due to the methoxy and piperidyl groups
Further Research
Required to understand its exact function and potential applications thoroughly.
Check Digit Verification of cas no
The CAS Registry Mumber 75902-76-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,9,0 and 2 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 75902-76:
(7*7)+(6*5)+(5*9)+(4*0)+(3*2)+(2*7)+(1*6)=150
150 % 10 = 0
So 75902-76-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H25N3O4/c1-19-18(22)20-16-15(25-11-9-21-7-4-3-5-8-21)12-14-13(6-10-24-14)17(16)23-2/h6,10,12H,3-5,7-9,11H2,1-2H3,(H2,19,20,22)
75902-76-0Relevant academic research and scientific papers
Synthesis and Antiarrhythmic Activity of New Benzofuran Derivatives
Bourgery, Guy,Dostert, Philippe,Lacour, Alain,Langlois, Michel,Pourrias, Bernard,Tisne-Versailles, Jacky
, p. 159 - 167 (2007/10/02)
Various 5-aminobenzofuran derivatives were prepared from khellin and screened intravenously in the dog for their potential antiarrhythmic activity against ouabain-induced ventricular arrhythmia and in the Harris test.From systematic structural variations it was found that two methoxy groups in positions 4 and 7 on the benzofuran ring, a tertiary aminoethoxy side chain in position 6, and a N-methylurea group in position 5 led to the most active compounds.These were then tested orally in the Harris test in the dog.The two long-acting derivativesN--N'-methylurea (8j) and N--N'-methylurea (8m) showed advantages when compared to quinidine and diisopyramide and have been selected for further studies.
