75919-94-7Relevant articles and documents
One-pot synthesis of ortho-acylphenols by palladium-catalyzed phenol C–H addition to nitriles
Jiang, Tao-Shan,Gan, Bei,Wang, Xi,Zhang, Xiuli
supporting information, p. 4197 - 4199 (2017/10/06)
The regioselective one-pot synthesis of ortho-acylphenols via the palladium-catalyzed addition of phenols to nitriles and subsequent hydrolysis is reported. The acylation reaction proceeded smoothly using the Pd(OAc)2/DMSO system and TFA as the additive. This method also provides a direct strategy for the synthesis of a salicylketoxime scaffold.