Cas 75933-89-0,Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester

75933-89-0

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Basic information

Product Name: Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester
Synonyms: Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester
CAS NO:75933-89-0
Molecular Formula:
Molecular Weight: 783.559
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester(CAS DataBase Reference)
NIST Chemistry Reference: Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester(75933-89-0)
EPA Substance Registry System: Phosphoric acid (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester(75933-89-0)

Safety Data

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Safety Statements: N/A
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HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 75933-89-0(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 75933-89-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,9,3 and 3 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 75933-89:
(7*7)+(6*5)+(5*9)+(4*3)+(3*3)+(2*8)+(1*9)=170
170 % 10 = 0
So 75933-89-0 is a valid CAS Registry Number.

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75933-89-0Relevant academic research and scientific papers

Synthesis of Bis(5-chloro-8-quinolyl) Nucleoside 5'-Phosphates in Oligoribonucleotide Synthesis by the Phosphotriester Approach

Takaku, Hiroshi,Kamaike, Kazuo,Kasuga, Kenichi

, p. 4937 - 4940 (2007/10/02)

A new phosphorylating agent, bis(5-chloro-8-quinolyl) phosphate was found to be a useful agent for the phosphorylation of the 5'-hydroxyl group of unprotected nucleosides.This agent smoothly reacts with 3',5',-unprotected nucleosides in the presence of 8-quinolinesulfonyl tetrazolide (QS-t) to give the corresponding bis(5-chloro-8-quinolyl) nucleoside 5'-phosphates in good yields without 3'-mono- and 3',5'-diphosphorylated products.They are key intermediates for the synthesis of oligoribonucleotides bearing 5'-terminal phosphate.Zinc chloride can be used as an effective and mild agent for removal of 5-chloro-8-quinolyl group.

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