759442-73-4

Usage

Spiro compound

Unique carbon framework

Methyl group

Attached to the ring
A methyl group (CH3) is a hydrocarbon group consisting of one carbon atom bonded to three hydrogen atoms. In 1,3-Diazaspiro[4.4]non-1-en-4-one, 2-methyl- (9CI), a methyl group is attached to the spiro ring.

Physical state

Pale yellow liquid at room temperature
The compound exists as a pale yellow liquid under normal conditions, which is important for its handling and storage.

Organic synthesis

Used in various processes
1,3-Diazaspiro[4.4]non-1-en-4-one, 2-methyl- (9CI) is utilized in different organic synthesis processes, which involve the formation of new chemical compounds from simpler precursors.

Building block

Preparation of other organic compounds
It serves as a building block for the preparation of other organic compounds, making it a valuable intermediate in chemical synthesis.

Pharmaceutical research

Potential applications
Due to its unique structure and properties, 1,3-Diazaspiro[4.4]non-1-en-4-one, 2-methyl- (9CI) may have potential applications in the field of pharmaceutical research and development, possibly leading to the discovery of new drugs or therapies.

Chemical classification

9CI
The 9CI (Chemical Abstracts Service Registry Number) is a unique identifier assigned to this specific compound, allowing for easy reference and identification in scientific literature and databases.

Upstream product

• 4854-56-2 1-acetamidocyclopentane-1-carboxamide 
• 17193-28-1 1-aminocyclopentane-1-carboxamide 
• 78388-61-1 cycloleucine methyl ester 
• 1000-84-6 O-ethyl acetimidate 

Relevant academic research and scientific papers

4. 4 - Disubstituted - 4, 5 - dihydro - 1H - imidazole -5 - ketone, derivative and its synthesis method

The invention relates to a 4, 4-disubstituted-4, 5-dihydro-1H-imidazole-5-one and derivatives thereof as well as a synthesis method thereof. The synthesis method adopts the technical scheme that amidine compounds and ketones are converted into imidazolone and derivatives thereof in the absence of catalysts just under the action of alkali by using air or oxygen as an oxidant and pyridine, quinoline, triethylamine, NMP, DMA, DMSO, 1, 4-dioxane, toluene and the like as an organic solvent. The synthesis method overcomes the difficulties of the existing method for synthesizing imidazolone compounds of complicated synthesis steps, multi-step synthesis processes as well as the use of metal catalysts, metal oxidants or peroxides of chemical equivalent; and 4, 4-disubstituted-4, 5-dihydro-1H-imidazole-5-one and the derivatives thereof are suitably used as multifunctional materials, and are important raw materials especially for producing the medicine Avapro for treating high blood pressure.

BIARYLMETHYL HETEROCYCLES

The present invention provides compounds of Formula (I): wherein all variables are as defined in the specification, and compositions comprising any of such novel compounds. These compounds are biased agonists, or β-Arrestin agonists of the angiotensin II receptor, which may be used as medicaments.

SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES

The present invention relates to polysubstituted imidazolone derivatives, to the pharmaceutical compositions comprising them and to the therapeutic uses thereof in the human and animal health fields. The present invention also relates to a process for preparing these derivatives.