75962-07-1Relevant academic research and scientific papers
Preparation and physical properties of alkylcobalt complexes of the coenzyme B12 model complex RCo[C2(DO)(DOH)pn]X
Finke, Richard G.,Smith, Brad L.,McKenna, William A.,Christian, Paul A.
, p. 687 - 693 (1981)
A detailed and convenient three-step synthesis of Co[C2(DO)(DOH)pn]I2 (IV) is described beginning with readily available starting materials. The 70-80% reduction of the diiodide IV to 1-g quantities of the crystalline Co(I) Co[C2(DO)(DOH)pn](CO) (V) is presented as are the 13CO-exchange reaction of V and its alkyl halide oxidative additions as a clean and efficient synthesis of RCo[C2(DO)(DOH)pn]X complexes. Transformation of the alkyl halide adducts to [RCo[C2(DO)-(DOH)pn](base)]+PF6 - and BF2-bridged derivatives is also described. Some of the key physical properties of the alkyl-cobalt complexes are also presented including their extent of axial halide dissociation, the pyridine binding constant of the methyl derivative, the photochemical cleavage of the alkyl-cobalt bond in the presence of HMn(CO)5, and the properties of the oxime O?H?O bridge.
