7597-43-5

Basic information

• Product Name: 2-phenyl-2,3-dihydro-1H-1,3,2-benzodiazaphosphole 2-oxide
• CAS NO: 7597-43-5
• Molecular Formula: C₁₂H₁₁N₂OP
• Molecular Weight: 230.2023
• Mol File: 7597-43-5.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 388°C at 760 mmHg
• Flash Point: 188.5°C
• Density: 1.33g/cm³
• Vapor Pressure: 3.16E-06mmHg at 25°C
• Refractive Index: 1.656
• CAS DataBase Reference: 2-phenyl-2,3-dihydro-1H-1,3,2-benzodiazaphosphole 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-2,3-dihydro-1H-1,3,2-benzodiazaphosphole 2-oxide(7597-43-5)
• EPA Substance Registry System: 2-phenyl-2,3-dihydro-1H-1,3,2-benzodiazaphosphole 2-oxide(7597-43-5)

Safety Data

• Hazardous Substances Data: 7597-43-5(Hazardous Substances Data)

Upstream product

• 644-97-3 Dichlorophenylphosphine 
• 95-54-5 1,2-diamino-benzene 
• 824-72-6 P,P-dichlorophenylphosphine oxide 

Relevant articles and documents

Microwave-assisted synthesis and diabetic/antioxidant assessments of 1,3,2-benzothiazaphosphole-3(2H)-carbothioamide- and -diazaphosphole-3(2H)-dicarbothioamide 2-oxide derivatives

Abstract: Environmentally friendly synthesis of 1,3,2-benzothiazaphosphole-3(2H)-carbothioamide and -diazaphosphole-3(2H)-dicarbothioamide 2-oxides or the carboxamide 2-oxide analogs was reported. The targets were accomplished via a two step process: (1) preparation of the substrates 2-phenyl-2,3-dihydro-1H-1,3,2-benzothiazaphosphole 2-oxide and -1,3,2-benzodiazaphosphole 2-oxide; (2) exploiting these two phospholes in reactions with various saturated and unsaturated isothiocyanates and some isocyanate analogs in dry DMF/pyridine under microwave irradiation thereby isolating the target compounds in 85–95?% yields. Based upon computer-assisted molecular model (CAMM), new compounds were screened for their antidiabetic and antioxidant properties and many of them exhibited moderate to high in vivo and in vitro diabetic and/or antioxidant potencies. Graphical abstract: [Figure not available: see fulltext.]