75987-20-1

Basic information

• Product Name: 3-(4'-Hydroxybenzyl)pyridine
• Synonyms: 3-(4'-Hydroxybenzyl)pyridine
• CAS NO: 75987-20-1
• Molecular Weight: 185.225
• Mol File: 75987-20-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3-(4'-Hydroxybenzyl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(4'-Hydroxybenzyl)pyridine(75987-20-1)
• EPA Substance Registry System: 3-(4'-Hydroxybenzyl)pyridine(75987-20-1)

Safety Data

• Hazardous Substances Data: 75987-20-1(Hazardous Substances Data)

Upstream product

• 85666-15-5 4-(3'-Pyridinylmethyl)aniline 
• 100-55-0 3-hydroxymethylpyridin 
• 128-39-2 2,6-di-tert-butylphenol 
• 91258-43-4 3-(4-methoxybenzyl)pyridine 
• 32361-76-5 3-(4'-nitrobenzyl)pyridine 

Downstream Products

• 103574-12-5 2-[4-(Pyridin-3-ylmethyl)phenyloxy]ethanol 
• 85666-04-2 3-(3-formyl-4-hydroxybenzyl)pyridine 
• 85666-17-7 furegrelate sodium 
• 85666-43-9 3-bromo-2-hydroxy-5-(3-pyridylmethyl)benzaldehyde 
• 549510-97-6 4-Hydroxy-piperidine-1-carboxylic acid 4-pyridin-3-ylmethyl-phenyl ester 
• 179020-09-8 3-[4-(3-chloro-propoxy)-benzyl]-pyridine 

Relevant articles and documents

Iridium-Catalyzed C4-Alkylation of 2,6-Di-tert-butylphenol by Using Hydrogen-Borrowing Catalysis

An iridium-catalyzed hydrogen-borrowing process has been developed whereby 2,6-di-tert-butylphenol can be alkylated at the C4-position by using a range of primary alcohols (11 examples, 40-93% yield). Following this, a selection of the products obtained underwent retro-Friedel-Crafts reactions to provide para-substituted phenols, which could potentially undergo further synthetic manipulations.

LTA4 Hydrolase inhibitors

The present invention provides compounds of the formula Ar1-Q-Ar2-Y-R-Z and pharmaceutically acceptable salts thereof wherein Ar1 and Ar2 are optionally substituted aryl moieties, Z is an optionally substituted nitrogen-containing moiety which may be an acyclic, cyclic or bicyclic amine or an optionally substituted monocyclic or bicyclic nitrogen-containing heteroaromatic moiety; Q is a linking group capable of linking two aryl groups; R is an alkylene moiety; Y is a linking moiety capable of linking an aryl group to an alkylene moiety and wherein Z is bonded to R through a nitrogen atom. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of inflammatory diseases which are mediated by LTB4 production, such as proriasis, ulcerative colitis, IBD and asthma.

Pyridyl-substituted-benzofurans

The present invention provides novel pyridinyl-benzofurans and derivatives thereof which are useful as thromboxane A2 (TXA2) synthetase inhibitors and as such represent potent pharmacological agents.