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2-(4-Benzyloxy-3-chloro-phenyl)-propionic acid is a chemical compound with the molecular formula C16H15ClO3. It is a derivative of propionic acid, featuring a benzyloxy group attached to a chlorophenyl ring. 2-(4-Benzyloxy-3-chloro-phenyl)-propionic acid is characterized by a 3-chloro substituent on the phenyl ring and a 4-benzyloxy group, which contributes to its unique chemical properties. It is a white crystalline solid and is used in the synthesis of various pharmaceuticals and agrochemicals due to its potential biological activity. The compound's structure allows for further functionalization and modification, making it a valuable intermediate in organic chemistry.

75987-60-9

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75987-60-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 75987-60-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,9,8 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 75987-60:
(7*7)+(6*5)+(5*9)+(4*8)+(3*7)+(2*6)+(1*0)=189
189 % 10 = 9
So 75987-60-9 is a valid CAS Registry Number.

75987-60-9Relevant academic research and scientific papers

The SAR analysis of TRPV1 agonists with the α-methylated B-region

Cho, Yongsung,Kim, Myeong Seop,Kim, Ho Shin,Ann, Jihyae,Lee, Jeewoo,Lee, Jiyoun,Pearce, Larry V.,Pavlyukovets, Vladimir A.,Morgan, Matthew A.,Blumberg, Peter M.

, p. 5227 - 5231 (2012/09/07)

A series of TRPV1 agonists with amide, reverse amide, and thiourea groups in the B-region and their corresponding α-methylated analogues were investigated. Whereas the α-methylation of the amide B-region enhanced the binding affinities and potencies as agonists, that of the reverse amide and thiourea led to a reduction in receptor affinity. The analysis indicated that proper hydrogen bonding as well as steric effects in the B-region are critical for receptor binding.

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