75989-58-1

Upstream product

• 497-18-7 carbonodihydrazide 
• 75989-72-9 ethyl-2-(1-ethoxy-2-phenylethylidene)hydrazine carboxylate 
• 209797-63-7 Formic acid [1-ethoxy-2-phenyl-eth-(E)-ylidene]-hydrazide 

Downstream Products

• 137182-51-5 3-benzyl-4-o-hydroxybenzylidenamino-4,5-dihydro-1,2,4-triazol-5-one 

Relevant academic research and scientific papers

Synthesis and in vitro antioxidant and antimicrobial activities of novel 3-alkyl(aryl)-4-[3-methoxy-4-(2-furylcarbonyloxy)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones, and their N-acetyl, N-Mannich base derivatives

The reactions of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (1) with 3-methoxy-4-(2-furylcarbonyloxy)-benzaldehyde (2) formed 3-alkyl(aryl)-4-[3-methoxy-4-(2-furylcarbonyloxy)-benzylidenamino]-4,5-dihydro-1H-1,2,4-triazol-5-ones (3). Moreov

In vitro antioxidant and antimicrobial properties of some new 4,5-dihydro-1H-1,2,4-triazole-5-ones

In this study, 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (3a-3h) reacted with 3-benzenesulfonyloxy-4-methoxybenzaldehyde (1a-1h) to afford eight new 3-alkyl(aryl)-4-(3-benzenesulfonyloxy-4-methoxybenzylidenamino)-4,5-dihydro-1H-1,2,4-triaz

Synthesis, in vitro antimicrobial and antioxidant activities of some new 4,5-dihydro-1h-1,2,4-triazol-5-one derivatives

A series of compounds derived from 4,5-dihydro-1H-1,2,4-triazol-5-one were synthesized and characterized by spectral data. The 12 new compounds were analyzed for their potential in vitro antioxidant activities by three different methods. Compound 4f showe

Use of ester formylhydrazones for the synthesis of 1,2,4-triazole and 1,3,4-oxadiazole derivatives

A series of ester formylhydrazones were synthesised by the reaction of alkyl imidate hydrochlorides with ormylhydrazine. Treatment of the ester formylhydrazones with acetic acid hydrazide, isonicotinic acid hydrazide, nicotinicacid hydrazide, and 4-hydroxybenzhydrazide resulted in the formation of either 4-acylamino-4H-1,2,4-triazoles or 2,5-disubstituted 1,3,4-oxadiazoles. 3-Alkyl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesised by the reaction of the ester formylhydrazones with carbohydrazide. Some arylidenamino compounds were synthesized by the reaction of 4-amino-4,5-dihydro-1H-1,2,4- triazol-5-ones with several aldehydes. These compounds were characterised by elemental analyses, IR, 1H NMR, and UV spectral techniques.

Study of antioxidant properties and DNA interaction of some novel 4,5-Dihydro-1H-1,2,4-triazol-5-one derivatives

3-Alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) reacted with 4-benzenesulfonyloxybenzaldehyde (3) to afford the corresponding seven novel 3-alkyl(aryl)-4-(4-benzenesulfonyloxybenzylidenamino)-4,5-dihydro-1H-1,2, 4-triazol-5-ones (4). The ace

Synthesis of novel triazol compounds containing isatin as potential antibacterial and antifungal agents by microwave and conventional methods

Microwave irradiation has been used to accelerate the conversion of isatin (1a) and 5-nitroisatin (1b) into their Schiff bases 3-[5′-aryl(alkyl)- 2′,4′-dihydro-1′,2′,4′-triazol-3′-on- 4′-yl]iminoisatin (3a-g) and 3-[5′-aryl(alkyl)-2′,4′- dihydro-1′,2′,4′-triazol-3′-on-4′-yl] imino-5-nitroisatin (4a-g), respectively. Reaction was achieved by microwave-induced technique, which reduced the reaction time drastically and improved the yield when compared to conventional heating. The newly synthesised bases showed moderate antimicrobial activity against the standard bacterial and fungal organisms tested.

Synthesis and in-vitro antioxidant evaluation of some novel 4-(4-substituted) benzylidenamino-4,5-dihydro-1H-1,2,4-triazol-5-ones

3-Alkyl (aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2a-g) were reacted with 4-ethylbenzaldehyde to afford the corresponding 3-alkyl (aryl).4-(4-ethylbenzylidenamino)-4,5-dihydro-1H-1,2.4-triazol-5-ones (3a-g). The acetylation reactions of compound

Synthesis and in vitro antioxidant evaluation of some novel 4, 5-dihydro-1h-1, 2, 4-triazol-5-one derivatives

In this study, thirteen novel 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives were synthesized and characterized by elemental analyses and IR, 1H NMR,13C NMR and UV spectral data. The synthesized compounds were analyzed for their in v

Determination of the protonation constants of some 4-(substituted benzylamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones by the potentiometric method in ethanol-water mixtures

To gain more information about the effect of solvent on 4,5-dihydro-1H-1,2,4-triazol-5-ones, the stoichiometric protonation constants of thirteen triazoles in ethanol-water mixtures were determined at an ionic strength of 0.10MNaCl and at 25.0 ± 0.1°C und

Synthesis and non-aqueous medium titrations of some new 4-benzylidenamino-4,5-dihydro-1H-1,2,4-triazol-5-one derivatives

The synthesis of 3-alkyl(aryl)-4-(3-ethoxy-4-hydroxybenzylidenamino)-4,5- dihydro-1H-1,2,4-triazol-5-ones 3 from the reactions of 3-alkyl(aryl)-4-amino-4, 5-dihydro-1H-1,2,4-triazol-5-ones 2 with 3-ethoxy-4-hydroxybenzaldehyde is described. The acetylatio