75996-23-5Relevant academic research and scientific papers
A Practical Catalytic Method for the Preparation of Steroidal 1,4-Dien-3-ones by Oxygen Atom Transfer from Iodoxybenzene to Diphenyl Diselenide
Barton, Derek H. R.,Godfrey, Christopher R. A.,Morzycki, Jacek W.,Motherwell, William B.,Ley, Steven V.
, p. 1947 - 1952 (2007/10/02)
The dehydrogenation of steroidal 3-ketones can be accomplished in high yield using benzeneseleninic anhydride generated in situ by efficient oxygen atom transfer from iodoxybenzene to catalytic amounts of diphenyl diselenide.An experimentally convenient and economical development of this catalytic cycle is the use of meta-iodoxybenzoic acid which both avoids chromatography and allows recovery of meta-iodobenzoic acid and diphenyl diselenide. 12-Hydroxy- and 12-keto-steroids are also dehydrogenerated very efficiently using this catalytic process.
Removal of Thioacetal Protecting Groups by Benzeneseleninic Anhydride
Cussans, Nigel J.,Ley, Steven V.,Barton, Derek H. R.
, p. 1654 - 1657 (2007/10/02)
A number of thioacetals were deprotected with benzeneseleninic anhydride in good yield.The reaction worked particularly well for hindered spiro-1,3-dithiolans of 2,2,6-trimethylcyclohexanone and fenchone, and in examples where other literature methods had failed.
