75996-32-6

Upstream product

• 343226-26-6 3-benzyloxy-5-methoxybenzamide 
• 16618-67-0 3-bromo-5-nitroanisole 
• 7145-49-5 3-methoxy-5-nitrophenol 
• 75996-33-7 3-benzoxy-5-methoxybenzoyl chloride 
• 100-44-7 benzyl chloride 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 19520-75-3 3-hydroxy-5-methoxybenzoic acid 
• 50637-26-8 methyl 3-(benzyloxy)-5-methoxybenzoate 
• 50637-27-9 3-(benzyloxy)-5-methoxybenzoic acid 
• 535972-72-6 (3-benzyloxy-5-methoxy-phenyl)-carbamic acid tert-butyl ester 

Downstream Products

• 535972-41-9 1-[3-(8-bromo-octyloxy)-5-methoxy-phenyl]-7-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (3,5-difluoro-phenyl)-ethyl-amide 
• 535969-62-1 1-[3-(6-iodo-hexyloxy)-5-methoxy-phenyl]-7-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (3,5-difluoro-phenyl)-ethyl-amide 
• 535969-88-1 1-[3-(7-bromo-heptyloxy)-5-methoxy-phenyl]-7-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (3,5-difluoro-phenyl)-ethyl-amide 
• 535969-58-5 1-[3-(4-chloromethyl-benzyloxy)-5-methoxy-phenyl]-7-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (3,5-difluoro-phenyl)-ethyl-amide 
• 535969-55-2 1-(3-benzyloxy-5-methoxy-phenyl)-7-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (3,5-difluoro-phenyl)-ethyl-amide 
• 535969-56-3 1-(3-hydroxy-5-methoxy-phenyl)-7-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid (3,5-difluoro-phenyl)-ethyl-amide 
• 535969-54-1 1-(3-benzyloxy-5-methoxy-phenyl)-7-methoxy-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid 

Relevant academic research and scientific papers

IRAK DEGRADERS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

A novel class of apical sodium-dependent bile acid transporter inhibitors: The amphiphilic 4-oxo-1-phenyl-1,4-dihydroquinoline derivatives

A series of 4-oxo-1-phenyl-1,4-dihydroquinolines possessing a linker and an ammonio moiety were synthesized and found to inhibit the apical sodium-dependent bile acid transporter (ASBT). The potency of ASBT inhibition varied with the position and length o

Long-chain Phenols. Part 16. A Novel Synthesis of Homologous Orsellinic Acids and their Methyl Ethers

By the novel reaction of 3,5-dimethoxyfluorobenzene with n-alkyl-lithium compounds, followed by carbonation, homologous orsellinic acid dimethyl ethers (6-alkyl-2,4-dimethoxybenzoic acids) have been obtained.The reactions proceeded best with the homologues of methyl-lithium.These reactions are considered to occur by way of 3,5-dimethoxybenzyne. 2,4-Dimethoxyfluorobenzene did not form an aryne but gave 3-fluoro-2,6-dimethoxybenzoic acid instead.Decomposition with water of alkyl-lithium reaction mixtures from 3,5-dimethoxyfluorobenzene yielded 5-n-alkylresorcinol dimethyl ethers.Demethylaton of 6-alkyl-2,4-dimethoxybenzoic acids with boron trichloride proceeded partially and selectively to give the 6-alkyl-2-hydroxy-4-methoxybenzoic acids, and completely with aluminium chloride to give the homologous orsellinic acids.Boron tribromide was less effective, but readily gave the 5-alkyl resorcinols from the corresponding dimethyl ethers.