76003-45-7

Basic information

• Product Name: Butanedioic acid, fluoro-, dimethyl ester, (R)- (9CI)
• Synonyms: Butanedioic acid, fluoro-, dimethyl ester, (R)- (9CI)
• CAS NO: 76003-45-7
• Molecular Formula: C₆H₉FO₄
• Molecular Weight: 164.1316632
• Product Categories: ESTER
• Mol File: 76003-45-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Butanedioic acid, fluoro-, dimethyl ester, (R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Butanedioic acid, fluoro-, dimethyl ester, (R)- (9CI)(76003-45-7)
• EPA Substance Registry System: Butanedioic acid, fluoro-, dimethyl ester, (R)- (9CI)(76003-45-7)

Safety Data

• Hazardous Substances Data: 76003-45-7(Hazardous Substances Data)

Upstream product

• 617-55-0 dimethyl (S)-malate 

Relevant articles and documents

Synthesis, Absolute Configuration, and Circular Dichroism of the Enantiomers of Fluorosuccinic Acid

Diethylaminosulphur trifluoride (DAST) converts (2S)- and (2R)-malate esters into the enantiomeric fluorosuccinate esters. (2S,3R)-Malate, obtained from fumarate by fumarase-catalysed hydration in deuterium oxide, was used to show that the reaction with DAST occurs stereospecifically with inversion of configuration.Conversion of (2S)-aspartic acid into fluorosuccinate with sodium nitrite in polyhydrogen fluoride-pyridine occurs predominantly with retention of configuration.The circular dichroic spectra of (2S)- and (2R)-fluorosuccinic acids and their methyl esters are 'anomalous' and consequently the absolute configuration previously assigned to a Pseudomonal metabolite, (+)-fluorosuccinic acid, is shown to be erroneous.