76005-89-5Relevant academic research and scientific papers
Enamidines. Part 1. Synthesis of Enamidines and Dihydrotriazines by the Reaction of Organolithium and Organomagnesium Compounds with Aromatic Nitriles
Cook, Lawrence S.,Wakefield, Basil J.
, p. 2392 - 2397 (2007/10/02)
The reaction of alkyl-lithium compounds, possessing α-hydrogens, or benzylmagnesium chloride with aromatic nitriles, followed by hydrolysis, gives ketones, E- and Z-N1-(arylalk-1-enyl)benzamidines, 2-alkyl-2,4,6-triaryldihydro-1,3,5-triazines, and 2,4,6-triaryl-1,3,5-triazines.Conditions for preparing the enamidines in useful yields were established. t-Butyl-lithium and phenyl-lithium with benzonitrile gave only the ketones and dihydrotriazines.Phenylmagnesium bromide gave only benzophenone.
