76006-15-0Relevant academic research and scientific papers
Synthesis, reactivity and 13C-NMR of 1H-pyrazolo[3,4-c]pyridine derivatives
Milhavet, Jean-Claude,Gueiffier, Alain,Bernal, Lysiane,Teulade, Jean-Claude
, p. 1661 - 1667 (2007/10/03)
The synthesis of various 1H-pyrazolo [.-c.]pyridines was reported. 3- Cyano derivatives were obtained from the corresponding nitro compounds by Sandmeyer Reaction using Na3[Cu(CN)4] at pH 1. The 13C-NMR data of this series were also described.
Pyrazolopyridines. Part 5. Preparation and Reactions of Pyrazolopyridines
Chapman, David,Hurst, Jim
, p. 2398 - 2404 (2007/10/02)
A series of pyrazolopyridines has been prepared by nitrosation of 3-acetamido-4-methylpyridines and subsequent rearrangement and cyclisation of the N-acetyl-N-nitroso-compounds produced.The reactions of the pyrazolopyridines have been investigated. 1- and 2-Acetyl and 1- and 2-benzyl compounds were obtained and their structures elucidated spectroscopically.The ring system readily undergoes electrophilic substitution in the 3-position. 7-Chloropyrazolopyridine has been shown to be more susceptible to nucleophilic substitution than the isomeric 5-chloro-compound.
