76007-16-4

Upstream product

• 38205-60-6 5-acetyl-2,4-dimethylthiazole 

Downstream Products

• 76007-22-2 2,4-dimethyl-5-N-methylanilinoacetylthiazole 
• 1377581-84-4 (5-bromo-2-methoxy-phenyl)-(2',4'-dimethyl-[4,5']bithiazolyl-2-yl)-amine 
• 1377579-28-6 3-(2',4'-Dimethyl-[4,5']bithiazolyl-2-ylamino)-4-trifluoromethoxy-benzamide 
• 1377581-85-5 (2',4'-Dimethyl-[4,5']bithiazolyl-2-yl)-[2-methoxy-5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-phenyl]-amine 
• 1377579-12-8 3-(5-Bromo-2',4'-dimethyl-[4,5']bithiazolyl-2-ylamino)-4-isopropoxy-benzamide 
• 1377579-23-1 3-(2',4'-Dimethyl-[4,5']bithiazolyl-2-ylamino)-4-propoxy-benzamide 
• 1377579-27-5 3-(2',4'-Dimethyl-[4,5']bithiazolyl-2-ylamino)-4-(2,2,2-trifluoro-ethoxy)-benzamide 
• 1377581-20-8 1-{5-[3-(2',4'-Dimethyl-[4,5']bithiazolyl-2-ylamino)-4-methoxy-phenyl]-thiophen-2-yl}-ethanone 
• 1377581-21-9 (2',4'-Dimethyl-[4,5']bithiazolyl-2-yl)-[5-(3,5-dimethyl-isoxazol-4-yl)-2-methoxy-phenyl]-amine 
• 1377581-97-9 3-(2',4'-dimethyl-[4,5']bithiazolyl-2-ylamino)-4-hydroxy-benzamide 
• 1377580-12-5 3-(2',4'-Dimethyl-[4,5']bithiazolyl-2-ylamino)-4-isopropoxy-benzoic acid 
• 1377583-46-4 3-(2',4'-dimethyl-[4,5']bithiazolyl-2-ylamino)-4-trifluoromethoxy-benzenesulfonamide 
• 1415233-06-5 (2',4'-Dimethyl-[4,5']bithiazolyl-2-yl)-(2-isopropoxy-phenyl)-amine 
• 1415233-10-1 (2',4'-Dimethyl-[4,5']bithiazolyl-2-yl)-(5-fluoro-2-methoxy-phenyl)-amine.HBr 

Relevant academic research and scientific papers

BISTHIAZOLE INHIBITORS OF PRO-MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to bisthiazole I and its therapeutic and prophylactic uses, wherein the variables A, R5, R6, and R7 are defined in the specification. Disorders treated and/or prevented include rheumatoid arthritis.

METHODS OF INHIBITING PRO MATRIX METALLOPROTEINASE ACTIVATION

This invention relates to methods for preventing, treating or ameliorating an MMP9 and/or MMP13 mediated syndrome, disorder or disease comprising administering to a subject in need thereof an effective amount of a compound listed in the examples section of this specification, or a form, composition or medicament thereof. Disorders treated and/or prevented include rheumatoid arthritis.